Summary | Transgene origin | Transgene description | Expression | Recombinase activity | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Tg(Mef2c-cre)2Blk
Name:	transgene insertion 2, Brian L Black
MGI ID:	MGI:3639735
Synonyms:	AHF-Cre, Mef2c-AHFCre, mef2c-AHF-Cre line 200A
Transgene:	Tg(Mef2c-cre)2Blk  Location: unknown
Alliance:	Tg(Mef2c-cre)2Blk page

Strain of Origin:

Not Specified

Transgene Type:    Transgenic (Recombinase) Mutation:    Insertion   Tg(Mef2c-cre)2Blk expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note Not Specified Mef2c   Mutation details: The Mef2c anterior heart field enhancer and promoter (AHF) was cloned into a cre expression plasmid with the cre cDNA and the SV40 splice sequence and the polyA signal sequence. The Mef2c-AHF-Cre fragment was injected into male pronuclei of fertilized oocytes. Three founder lines were initially characterized and line 200A was used for further analysis. (J:103545)

Activity:	Tissue activity of this recombinase allele
Driver:	Mef2c (species not specified) Summary of all recombinase alleles driven by Mef2c. Comparative matrix view of recombinase activities

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

145 assay results 5 RNA-Seq or microarray experiment(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:103545 Verzi MP, et al., The right ventricle, outflow tract, and ventricular septum comprise a restricted expression domain within the secondary/anterior heart field. Dev Biol. 2005 Nov 1;287(1):134-45
All:	82 reference(s)