About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:109566 Petit N, et al., Patterns of expression of the three cerebral cavernous malformation (CCM) genes during embryonic and postnatal brain development. Gene Expr Patterns. 2006 Jun;6(5):495-503
Assay type: RNA in situ
MGI Accession ID: MGI:3639609
Gene symbol: Pdcd10
Gene name: programmed cell death 10
Probe: Ccm3/Pdcd10
Probe preparation: Antisense labelled with S35 RNA
Assay notes: Fixative was 4% formalin.
Results
Specimen 1D: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: central nervous system Strong Graded 1D Expression is strongest in the posterior neural tube.

Specimen 1H: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: cerebral cortex intermediate zone Strong 1H
TS22: cerebral cortex ventricular layer Strong 1H
TS22: cortical plate Strong 1H
TS22: ganglionic eminence Strong 1H

Specimen 1L: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: basal columns Very strong 1L
TS22: dorsal root ganglion Strong 1L
TS22: alar columns Moderate 1L

Specimen Not Shown: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: medulla oblongata Present
TS22: midbrain roof plate Present
TS22: thalamus Present
TS22: brain vascular element Weak Regionally restricted Expression is in the small vessels of the pons.

Specimen 1P: postnatal day 8 (more )
Structure Level Pattern Image Note
TS28: brain Strong 1P Expression is in all neuronal layers throughout the brain.
TS28: cerebellum white matter Present 1P
TS28: corpus callosum Present 1P
TS28: hippocampus Present 1P

Specimen 1T: postnatal day 19 (more )
Structure Level Pattern Image Note
TS28: brain Strong 1T Expression is in all neuronal layers throughout the brain.
TS28: cerebellum Purkinje cell layer Very strong 1T
TS28: cerebellum external granule cell layer Weak 1T
TS28: cerebellum internal granule cell layer Weak 1T
TS28: cerebellum white matter Weak 1T
TS28: corpus callosum Weak 1T

Specimen 1X: postnatal day 19 (more )
Structure Level Pattern Image Note
TS28: retina ganglion cell layer Strong 1X
TS28: retina inner nuclear layer Strong 1X
TS28: retina outer nuclear layer Strong 1X

Specimen 1ZZ: postnatal adult (more )
Structure Level Pattern Image Note
TS28: brain Present 1ZZ Expression is in all neuronal layers throughout the brain.
TS28: cortical layer II Present 1ZZ
TS28: cortical layer III Present 1ZZ
TS28: cortical layer IV Present 1ZZ
TS28: cortical layer V Present 1ZZ
TS28: cortical layer VI Present 1ZZ
TS28: cortical layer I Absent 1ZZ

Specimen Not Shown: postnatal adult (more )
Structure Level Pattern Image Note
TS28: caudate-putamen Strong
TS28: main olfactory bulb mitral cell layer Strong
TS28: medulla oblongata Strong
TS28: pons Strong
TS28: thalamus Strong
TS28: main olfactory bulb glomerular layer Moderate
TS28: main olfactory bulb granule cell layer Moderate
TS28: cerebellum white matter Absent
TS28: corpus callosum Absent

Specimen Not Shown: postnatal day 8 (more )
Structure Level Pattern Image Note
TS28: cerebellum external granule cell layer Strong
TS28: cerebellum internal granule cell layer Strong
TS28: cerebellum Purkinje cell layer Weak

Specimen 2C: postnatal adult (more )
Structure Level Pattern Image Note
TS28: spinal cord gray matter Strong 2C
TS28: spinal cord white matter Absent 2C

Specimen 3D: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: cardinal vein Present 3D
TS17: dorsal aorta Present 3D
TS17: heart Present 3D

Specimen 3K: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: basilar artery Present 3K
TS22: dorsal aorta Present 3K
TS22: hemiazygos vein Present 3K
TS22: internal carotid artery Present 3K
TS22: superior vena cava Present 3K
TS22: umbilical artery Present 3K
TS22: umbilical vein Present 3K
TS22: vertebral artery Present 3K

Specimen 4C: postnatal day 8 (more )
Structure Level Pattern Image Note
TS28: central nervous system vascular element Present Regionally restricted 4C Expression is in meningeal vessels.

Specimen Not Shown: postnatal day 19 (more )
Structure Level Pattern Image Note
TS28: central nervous system vascular element Absent Expression is absent in meningeal vessels.

Specimen Not Shown: postnatal adult (more )
Structure Level Pattern Image Note
TS28: central nervous system vascular element Absent Expression is absent in meningeal vessels.

Specimen 6CC: postnatal day 8 (more )
Structure Level Pattern Image Note
TS28: brain blood vessel Present Regionally restricted 6CC Expression is in cerebral cortex vessels in regions with a lower neuronal cell density.

Specimen 7B: postnatal day 8 (more )
Structure Level Pattern Image Note
TS28: brain blood vessel Present Regionally restricted 7B Expression is in cerebral cortex vessels.

Specimen 7D: postnatal day 19 (more )
Structure Level Pattern Image Note
TS28: brain blood vessel Absent 7D Absent in cerebral cortex vessels.

Specimen 7F: postnatal adult (more )
Structure Level Pattern Image Note
TS28: brain blood vessel Absent 7F Absent in cerebral cortex vessels.

Specimen 8H: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: adrenal gland Strong 8H
TS22: intestine Strong 8H
TS22: liver Strong 8H
TS22: lung Strong 8H
TS22: metanephros Strong 8H
TS22: pancreas Strong 8H
TS22: thymus primordium Strong 8H


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/25/2025
MGI 6.24
The Jackson Laboratory