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Gene Expression Data
Assay Details
Assay
Reference: J:109566 Petit N, et al., Patterns of expression of the three cerebral cavernous malformation (CCM) genes during embryonic and postnatal brain development. Gene Expr Patterns. 2006 Jun;6(5):495-503
Assay type: RNA in situ
MGI Accession ID: MGI:3639588
Gene symbol: Krit1
Gene name: KRIT1, ankyrin repeat containing
Probe: Krit1 cDNA
Probe preparation: Antisense labelled with S35 RNA
Assay notes: Fixative was 4% formalin.
Results
Specimen 1B: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: central nervous system Strong Graded 1B Expression is strongest in the posterior neural tube.

Specimen 1F: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: cerebral cortex intermediate zone Strong 1F
TS22: cerebral cortex ventricular layer Strong 1F
TS22: cortical plate Strong 1F
TS22: ganglionic eminence Strong 1F

Specimen 1J: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: spinal cord Very strong 1J
TS22: dorsal root ganglion Strong 1J

Specimen Not Shown: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: medulla oblongata Present
TS22: midbrain roof plate Present
TS22: thalamus Present
TS22: brain vascular element Absent Absent in the brain vasculature.

Specimen 1N: postnatal day 8 (more )
Structure Level Pattern Image Note
TS28: cerebellum white matter Present 1N
TS28: corpus callosum Present 1N
TS28: hippocampus Present 1N
TS28: brain Present 1N Expression is in all neuronal layers throughout the brain.

Specimen 1R: postnatal day 19 (more )
Structure Level Pattern Image Note
TS28: cerebellum internal granule cell layer Very strong 1R
TS28: cerebellum Purkinje cell layer Present 1R
TS28: cerebellum external granule cell layer Present 1R
TS28: brain Present 1R Expression is in all neuronal layers throughout the brain.
TS28: cerebellum white matter Weak 1R
TS28: corpus callosum Weak 1R

Specimen 1V: postnatal day 19 (more )
Structure Level Pattern Image Note
TS28: retina ganglion cell layer Strong 1V
TS28: retina inner nuclear layer Strong 1V
TS28: retina outer nuclear layer Strong 1V

Specimen 1Z: postnatal adult (more )
Structure Level Pattern Image Note
TS28: brain Present 1Z Expression is in all neuronal layers throughout the brain.
TS28: cortical layer II Present 1Z
TS28: cortical layer III Present 1Z
TS28: cortical layer IV Present 1Z
TS28: cortical layer V Present 1Z
TS28: cortical layer VI Present 1Z
TS28: cortical layer I Absent 1Z

Specimen Not Shown: postnatal adult (more )
Structure Level Pattern Image Note
TS28: caudate-putamen Strong
TS28: main olfactory bulb mitral cell layer Strong
TS28: medulla oblongata Strong
TS28: pons Strong
TS28: thalamus Strong
TS28: main olfactory bulb glomerular layer Moderate
TS28: main olfactory bulb granule cell layer Moderate
TS28: cerebellum white matter Absent
TS28: corpus callosum Absent

Specimen Not Shown: postnatal day 8 (more )
Structure Level Pattern Image Note
TS28: cerebellum external granule cell layer Strong
TS28: cerebellum internal granule cell layer Strong
TS28: cerebellum Purkinje cell layer Weak

Specimen 2A: postnatal adult (more )
Structure Level Pattern Image Note
TS28: spinal cord gray matter Strong 2A
TS28: spinal cord white matter Absent 2A

Specimen 3B: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: cardinal vein Present 3B
TS17: dorsal aorta Present 3B
TS17: heart Present 3B

Specimen 3I: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: basilar artery Present 3I
TS22: dorsal aorta Present 3I
TS22: hemiazygos vein Present 3I
TS22: internal carotid artery Present 3I
TS22: superior vena cava Present 3I
TS22: umbilical artery Present 3I
TS22: umbilical vein Present 3I
TS22: vertebral artery Present 3I

Specimen Not Shown: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: aorta Absent
TS27: vein Absent

Specimen 4A: postnatal day 8 (more )
Structure Level Pattern Image Note
TS28: central nervous system vascular element Absent 4A Absent in meningeal vessels.

Specimen 6AA: postnatal day 8 (more )
Structure Level Pattern Image Note
TS28: brain blood vessel Absent 6AA Absent in cerebral cortex vessels.

Specimen 8B: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: adrenal gland Strong 8B
TS22: liver Strong 8B
TS22: lung Strong 8B
TS22: metanephros Strong 8B
TS22: thymus primordium Strong 8B
TS22: intestine Present 8B
TS22: pancreas Present 8B


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory