Shh RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:106931 Isono K, et al., Overlapping roles for homeodomain-interacting protein kinases hipk1 and hipk2 in the mediation of cell growth in response to morphogenetic and genotoxic signals. Mol Cell Biol. 2006 Apr;26(7):2758-71
Assay type:	RNA in situ
MGI Accession ID:	MGI:3629618
Gene symbol:	Shh
Gene name:	sonic hedgehog

Probe:

Shh probe53

Results

Specimen 6B 1-/-2+/+ top: embryonic day 9.5; Hipk1^tm1Hko/Hipk1^tm1Hko (more

)

Structure	Level	Pattern	Image	Note
TS15: embryo	Present		6B top left

Specimen 6B 1-/-2-/- top: embryonic day 9.5; Hipk1^tm1Hko/Hipk1^tm1Hko, Hipk2^tm1Hko/Hipk2^tm1Hko (more

)

Structure	Level	Pattern	Image	Note
TS15: embryo	Present		6B top right

Specimen 6B 1-/-2+/+ bottom: embryonic day 9.5; Hipk1^tm1Hko/Hipk1^tm1Hko (more

)

Structure	Level	Pattern	Image	Note
TS15: neural tube floor plate	Present		6B bottom left
TS15: notochord	Present		6B bottom left

Specimen 6B 1-/-2-/- bottom: embryonic day 9.5; Hipk1^tm1Hko/Hipk1^tm1Hko, Hipk2^tm1Hko/Hipk2^tm1Hko (more

)

Structure	Level	Pattern	Image	Note
TS15: notochord	Present		6B bottom right	Expression was unchanged in the notochord of the double mutant compared to the single mutant.
TS15: neural tube floor plate	Present		6B bottom right	Expression was reduced in the floor plate of the double mutant compared to the single mutant.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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