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Gene Expression Data
Assay Details
Assay
Reference: J:106710 Takemoto M, et al., Large-scale identification of genes implicated in kidney glomerulus development and function. EMBO J. 2006 Mar 8;25(5):1160-74
Assay type: RNA in situ
MGI Accession ID: MGI:3625907
Gene symbol: Nphs2
Gene name: nephrosis 2, podocin
Probe: Nphs2 probe1
Probe preparation: Antisense RNA
Results
Specimen 3A: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: renal cortex Present Regionally restricted 3A Nphs2 Expression is in glomerular podocytes.
Specimen 3C Comma: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: comma-shaped body Absent 3C Nphs2 Comma Expression is absent in the comma-shaped stage of nephron development.
Specimen 3C S-shaped: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: s-shaped body Present Regionally restricted 3C Nphs2 S-shaped Expression is in podocytes.
Specimen 3C Capillary loop: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: visceral epithelium of capillary loop renal corpuscle Present Regionally restricted 3C Nphs2 Capill loop Expression is in podocytes.
Specimen 3C Mature: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: visceral epithelium of mature renal corpuscle Present Regionally restricted 3C Nphs2 Mature Expression is in podocytes.
Specimen 8A +/+: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: glomerular tuft Present 8A Nphs2 +/+
Specimen 8A -/-: embryonic day 18.5; Foxc2tm1Miu/Foxc2tm1Miu (more )
Structure Level Pattern Image Note
TS26: glomerular tuft Weak 8A Nphs2 -/- Authors report a specific and strong downregulation of expression compared with wild type embryos.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/16/2024
MGI 6.23 		The Jackson Laboratory