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Tg(Alb1-HCVN)984Sml
Transgene Detail
Summary
Symbol: Tg(Alb1-HCVN)984Sml
Name: transgene insertion 984, Stanley M Lemon
MGI ID: MGI:3513782
Synonyms: FL-N/984
Transgene: Tg(Alb1-HCVN)984Sml  Location: unknown  
Alliance: Tg(Alb1-HCVN)984Sml page
Transgene
origin
Strain of Origin:  C3H x C57BL/6
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Mutation detailsA cDNA encoding the full open reading frame of the Japanese genotype 1b virus, HCV-N, was cloned between the murine albumin promoter-enhancer sequences and SV40 polyA sequence. The transgene was predicted to encode 10 distinct viral proteins. Transgene expression was detected in the liver. (J:63590)
Tumor Data
List all tumor models in MMHCdb carrying Tg(Alb1-HCVN)984Sml
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:63590 Lemon SM, et al., A transgenic mouse model of steatosis and hepatocellular carcinoma associated with chronic hepatitis C virus infection in humans. Trans Am Clin Climatol Assoc. 2000;111:146-56; discussion 156-7
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory