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In(4)56Rk
Radiation induced Allele Detail
Summary
Symbol: In(4)56Rk
Name: inversion, Chr 4, Roderick 56
MGI ID: MGI:3624517
Synonyms: Gbn1Rd4, Rd4
Gene: In(4)56Rk  Location: unknown  Genetic Position: Chr4, Syntenic
Mutation
origin
Strain of Origin:  (DBA/2J x C57BL/6J)F1
Mutation
description
Allele Type:    Radiation induced (Null/knockout)
Mutations:    Intragenic deletion, Inversion
  In(4)56Rk involves 1 genes/genome features (Gnb1) View all
 
Mutation detailsThis is a large inversion on Chromosome 4 which arose in a DBA/2J male exposed to 1000R of radiation. It covers most of chromosome 4 with the breakpoints in G bands 4A1 and 4E2. The distal breakpoint of the inversion is in the second intron of the Gnb1 gene and the proximal breakpoint lies within the centromere. (J:41514, J:108450)
Inheritance:    Semidominant
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 6 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any In(4)56Rk Mutation:  1 strain or line available
Notes
This inversion is homozygous lethal.
References
Original:  J:23392 Beechey CV, List of Chromosome Anomalies. Mouse Genome. 1994;92:336-47
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory