About   Help   FAQ
Gpat4Gt(DTM030)Byg
Gene trapped Allele Detail
Summary
Symbol: Gpat4Gt(DTM030)Byg
Name: glycerol-3-phosphate acyltransferase 4; gene trap DTM030, BayGenomics
MGI ID: MGI:3624276
Synonyms: Agpat6-, Agpat6Gt(pGT1dTMpfs)1Byg
Gene: Gpat4  Location: Chr8:23661281-23698362 bp, - strand  Genetic Position: Chr8, 11.42 cM
Alliance: Gpat4Gt(DTM030)Byg page
Mutation
origin
Mutant Cell Line:  DTM030
Germline Transmission:  Earliest citation of germline transmission: J:108166
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Gene trapped (Null/knockout, Reporter)
Mutation:    Insertion of gene trap vector     Vector: pGT1dTMpfs     Vector Type: secretory trap
 
Mutation details: A gene trap vector, pGT1dMpfs, containing a Betageo was inserted into intron 2 of the locus. Northern blot demonstrated lack of transcript in mutants. The insertion resulted in the production of an in-frame fusion transcript consisting of exons 1 and 2 from the locus and Betageo. (J:108166)
Sequence Tags: 
Sequence tag details (1 tag)
Genome Context: 
Genome Browser view of this mutation
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 16 assay results
In Structures Affected by this Mutation: 5 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gpat4 Mutation:  34 strains or lines available
Notes
All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.
References
Original:  J:108166 Beigneux AP, et al., Agpat6--a novel lipid biosynthetic gene required for triacylglycerol production in mammary epithelium. J Lipid Res. 2006 Apr;47(4):734-44
All:  11 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory