Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Prdm9tm1Ymat
Name:	PR domain containing 9; targeted mutation 1, Yasuhisa Matsui
MGI ID:	MGI:3623909
Synonyms:	Meisetz-
Gene:	Prdm9  Location: Chr17:15763341-15784616 bp, - strand  Genetic Position: Chr17, 8.95 cM
Alliance:	Prdm9tm1Ymat page

Germline Transmission:	Earliest citation of germline transmission: J:102875
Parent Cell Line:	E14 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A targeting vector containing the lacZ gene and a loxP-flanked PGKneo cassette disrupted part of exon 2, which contains the initiation codon, all of exons 3 to 6, and part of exon 7. RT-PCR analysis of testes from homozygous mutant mice did not detect transcript. (J:102875)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	9 assay results
In Structures Affected by this Mutation:	2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 3 strains available      Cell Lines: 0 lines available
Carrying any Prdm9 Mutation:	46 strains or lines available

Original:	J:102875 Hayashi K, et al., A histone H3 methyltransferase controls epigenetic events required for meiotic prophase. Nature. 2005 Nov 17;438(7066):374-8
All:	25 reference(s)