Tg(TTR-FOXM1)1Rhc
Transgene Detail
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| Symbol: |
Tg(TTR-FOXM1)1Rhc |
| Name: |
transgene insertion 1, Robert H Costa |
| MGI ID: |
MGI:2448259 |
| Synonyms: |
FoxM1B, TTR-HFH-11B |
| Transgene: |
Tg(TTR-FOXM1)1Rhc Location: unknown
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| Alliance: |
Tg(TTR-FOXM1)1Rhc page
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| Transgene Type: |
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Transgenic (Humanized sequence, Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(TTR-FOXM1)1Rhc expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Homolog in Mouse |
Note |
| human |
FOXM1 (2305) |
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Mutation details: The transgene consists of a TTR promoter and 2.6 kb of human FOXM1 sequence fused to TTR exon 2. The TTR regulatory region consists 3 kb of the TTR promoter, exon 1, and exon 2. This promoter construct targets transgene expression to hepatocytes.
(J:58603)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Three transgenic founders, T38, T69, and T70, were created. Founder T38 exhibited the highest level of transgene expression and was used for further analysis.
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| Original: |
J:58603 Ye H, et al., Premature expression of the winged helix transcription factor HFH-11B in regenerating mouse liver accelerates hepatocyte entry into S phase. Mol Cell Biol. 1999 Dec;19(12):8570-80 |
| All: |
4 reference(s) |
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Analysis Tools
