Tg(Mt1-GHRH)1Reh Transgene Detail MGI Mouse (MGI:2448617)

Tg(Mt1-GHRH)1Reh
Transgene Detail

Summary

Symbol:	Tg(Mt1-GHRH)1Reh
Name:	transgene insertion 1, Robert E Hammer
MGI ID:	MGI:2448617
Synonyms:	MT-hGHRH
Transgene:	Tg(Mt1-GHRH)1Reh Location: unknown
Alliance:	Tg(Mt1-GHRH)1Reh page

Transgene
origin

Strain of Origin:

(C57BL/6 x SJL)F2

Transgene
description

Transgene Type:

Transgenic (Inserted expressed sequence)

Mutation:

Insertion

Tg(Mt1-GHRH)1Reh expresses 1 gene

Mutation details: A mouse Mt1 promoter fused to a human GHRH minigene was used for the transgene. Northern blot analysis of transgenic livers confirmed expression of human GHRH mRNA. (J:81259)

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available

Notes

11 founder animals were created which sucessfully expressed human GHRH.

References

Original:	J:81259 Hammer RE, et al., Expression of human growth hormone-releasing factor in transgenic mice results in increased somatic growth. Nature. 1985 May 30-Jun 5;315(6018):413-6
All:	16 reference(s)

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