Tg(B2M)1Chmb
Transgene Detail
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| Symbol: |
Tg(B2M)1Chmb |
| Name: |
transgene insertion 1, Jeffrey W Chamberlain |
| MGI ID: |
MGI:2447342 |
| Transgene: |
Tg(B2M)1Chmb Location: unknown
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| Alliance: |
Tg(B2M)1Chmb page
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| Strain of Origin: |
either: (C57BL/6 and DBA/2) or (C57BL/6 and SJL)
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| Transgene Type: |
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Transgenic (Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(B2M)1Chmb expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Homolog in Mouse |
Note |
| human |
B2M (567) |
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Mutation details: A 14 kb genomic DNA fragment containing the entire human B2M sequence was used for the transgene. Transgene expression was confirmed by Northern blot analysis. The human transgene is over-expressed 2-fold with an expression pattern similar to that of the endogenous gene.
(J:80781)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:80781 Chamberlain JW, et al., Tissue-specific and cell surface expression of human major histocompatibility complex class I heavy (HLA-B7) and light (beta 2-microglobulin) chain genes in transgenic mice. Proc Natl Acad Sci U S A. 1988 Oct;85(20):7690-4 |
| All: |
3 reference(s) |
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Analysis Tools
