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Tg(MMTV-HPV16E6E7)263Gnk
Transgene Detail
Summary
Symbol: Tg(MMTV-HPV16E6E7)263Gnk
Name: transgene insertion 263, Gen Kondoh
MGI ID: MGI:3521865
Synonyms: HPV16 E6-E7, line 263
Transgene: Tg(MMTV-HPV16E6E7)263Gnk  Location: unknown  
Alliance: Tg(MMTV-HPV16E6E7)263Gnk page
Transgene
origin
Strain of Origin:  C57BL/6
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Mutation detailsThis transgene contains the MMTV LTR (mouse mammary tumor virus long terminal repeat) fused to the HPV16 E6 and E7 orf sequences. The polyA tail is from SV40. Mice possessed 4-5 copies of the transgene oriented in tandom head to tail fashion. The transgene followed Mendelian inheritance patterns. The transgene was inherited in Mendelian fashion. (J:93826)
Tumor Data
List all tumor models in MMHCdb carrying Tg(MMTV-HPV16E6E7)263Gnk
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:93826 Kondoh G, et al., Very high incidence of germ cell tumorigenesis (seminomagenesis) in human papillomavirus type 16 transgenic mice. J Virol. 1991 Jun;65(6):3335-9
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/06/2026
MGI 6.24
The Jackson Laboratory