Tg(MMTV-HPV16E6E7)181Gnk
Transgene Detail
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| Symbol: |
Tg(MMTV-HPV16E6E7)181Gnk |
| Name: |
transgene insertion 181, Gen Kondoh |
| MGI ID: |
MGI:3521863 |
| Synonyms: |
181 transgenic line, E6E7, HPV16 E6E7, HPV16 E6-E7, line 181, MMTV-LTR-HPV16E6E7 |
| Transgene: |
Tg(MMTV-HPV16E6E7)181Gnk Location: unknown
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| Alliance: |
Tg(MMTV-HPV16E6E7)181Gnk page
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| Transgene Type: |
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Transgenic (Inserted expressed sequence) |
| Mutation: |
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Insertion
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Mutation details: This transgene contains the MMTV LTR (mouse mammary tumor virus long terminal repeat) fused to the HPV16 E6 and E7 orf sequences. The polyA tail is from SV40. Mice possessed 4-5 head to tail copies of the transgene. The transgene followed a Mendelian pattern of inheritance. Transgene expression was detected in testicular tumors and the submandibular gland, but not in the lung or the spleen.
(J:93826)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:93826 Kondoh G, et al., Very high incidence of germ cell tumorigenesis (seminomagenesis) in human papillomavirus type 16 transgenic mice. J Virol. 1991 Jun;65(6):3335-9 |
| All: |
5 reference(s) |
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Analysis Tools
