Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Bmp2tm1.1Jfm
Name:	bone morphogenetic protein 2; targeted mutation 1.1, James F Martin
MGI ID:	MGI:3620971
Synonyms:	Bmp2null
Gene:	Bmp2  Location: Chr2:133394079-133404805 bp, + strand  Genetic Position: Chr2, 65.21 cM
Alliance:	Bmp2tm1.1Jfm page

Germline Transmission:	Earliest citation of germline transmission: J:99582
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutation:    Intragenic deletion   Mutation details: This allele is a derivative of Bmp2tm1Jfm in which exon 3 is deleted by Cre-mediated recombination. Mice carrying the Bmp2tm1Jfm allele were mated to Tg(Nes-cre)1Mrt mice (J:58999) and offspring were screened for the heritable deletion. PCR analysis confirmed deletion of exon 3. (J:99582)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Bmp2 Mutation:	26 strains or lines available

Original:	J:99582 Ma L, et al., Generation of a Bmp2 conditional null allele. Genesis. 2005 Jul;42(3):203-6
All:	3 reference(s)