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Gene Expression Data
Assay Details
Assay
Reference: J:104161 Hoekman MF, et al., Spatial and temporal expression of FoxO transcription factors in the developing and adult murine brain. Gene Expr Patterns. 2006 Jan;6(2):134-40
Assay type: RNA in situ
MGI Accession ID: MGI:3620151
Gene symbol: Foxo1
Gene name: forkhead box O1
Probe: Foxo1 cDNA2
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 1A,B: postnatal adult (more )
Structure Level Pattern Image Note
TS28: dentate gyrus granule cell layer Strong 1B , 1A

Specimen 1C,D: postnatal adult (more )
Structure Level Pattern Image Note
TS28: piriform cortex Present 1D , 1C
TS28: accumbens nucleus Present Patchy 1C , 1D Expression is in a subpopulation of the striatal neurons.
TS28: caudate-putamen Present Patchy 1C , 1D Expression is in a subpopulation of the striatal neurons.

Specimen 1E,F: postnatal adult (more )
Structure Level Pattern Image Note
TS28: hippocampus CA3 Strong Regionally restricted 1F , 1E Expression is in part of the ventral region of the CA3 pyramidal neurons, absent in dorsal CA3 neurons.
TS28: amygdala Present 1E , 1F
TS28: hippocampus Present 1E , 1F

Specimen Not Shown: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: body wall Present Regionally restricted Expression is in embryonic body structures but not in neuronal precursor cells.
TS20: central nervous system Absent

Specimen Not Shown: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: brain Present

Specimen 4A,B: embryonic day 16.5 (more )
Note: (B) represents a higher magnification of the boxed area shown in (A)
Structure Level Pattern Image Note
TS24: corpus striatum Strong 4A
TS24: olfactory epithelium Strong 4A
TS24: tooth epithelium Strong 4A
TS24: thalamus Strong Regionally restricted 4A Expression is in the anteroventral nucleus of the thalamus.
TS24: telencephalon Present Regionally restricted 4B , 4A Expression is in the hippocampal neuroepithelium absent in the dentate gyrus.

Specimen 4C,D: embryonic day 18.5 (more )
Note: (D) represents a higher magnification of the boxed area shown in (C)
Structure Level Pattern Image Note
TS26: hippocampus Strong Regionally restricted 4C , 4D Expression is in the subiculum and the CA3 field.
TS26: midbrain tegmentum Strong Regionally restricted 4C
TS26: corpus striatum Present 4C
TS26: thalamus Present Regionally restricted 4C Expression is in the anteroventral nucleus.
TS26: dentate gyrus Absent 4D , 4C


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory