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Gene Expression Data
Assay Details
Assay
Reference: J:103780 Maurer ME, et al., Endocytosis of megalin by visceral endoderm cells requires the Dab2 adaptor protein. J Cell Sci. 2005 Nov 15;118(Pt 22):5345-55
Assay type: Immunohistochemistry
MGI Accession ID: MGI:3617845
Gene symbol: Lrp2
Gene name: low density lipoprotein receptor-related protein 2
Antibody: anti-megalin
Detection system: Secondary antibody coupled to Alexa Fluor
Assay notes: This section is also stained with EEA1 as shown in assay MGI:3617842.
Results
Specimen 2F +/?: embryonic day 6.5; Dab2tm1.1Cpr/Dab2+ (more )
Note: Littermate control; embryos were either +/+ or +/-. Double labeled: green - Lrp2; red - Eea1 (assay MGI:3617842).
Structure Level Pattern Image Note
TS9: extraembryonic visceral endoderm Present 2F Expression is at the apical surface and in apical and basolateral vesicles.
Specimen 2H -/-: embryonic day 6.5; Dab2tm1.1Cpr/Dab2tm1.1Cpr (more )
Note: Double labeled: green - Lrp2; red - Eea1 (assay MGI:3617842).
Structure Level Pattern Image Note
TS9: extraembryonic visceral endoderm Present 2H Expression is at the apical surface.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/30/2024
MGI 6.23 		The Jackson Laboratory