Summary | Mutation origin | Mutation description | Expression | Phenotypes | Tumor data | Find Mice (IMSR) | References

Symbol:	Ctnnd1tm1Abre
Name:	catenin delta 1; targeted mutation 1, Albert B Reynolds
MGI ID:	MGI:3617486
Synonyms:	Ctnnd1fl, p120F
Gene:	Ctnnd1  Location: Chr2:84430415-84481109 bp, - strand  Genetic Position: Chr2, 49.45 cM
Alliance:	Ctnnd1tm1Abre page

Germline Transmission:	Earliest citation of germline transmission: J:105283
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: Exons 3-8 were flanked by loxP sites upon removal of a FRT-flanked neo cassette. Deletion of the floxed sequence would remove the four in-frame ATGs, causing a premature frame shift and termination of translation. (J:105283)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	39 assay results
In Structures Affected by this Mutation:	10 anatomical structure(s)

List all tumor models in MMHCdb carrying Ctnnd1tm1Abre

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ctnnd1 Mutation:	122 strains or lines available

Original:	J:105283 Davis MA, et al., Blocked acinar development, E-cadherin reduction, and intraepithelial neoplasia upon ablation of p120-catenin in the mouse salivary gland. Dev Cell. 2006 Jan;10(1):21-31
All:	33 reference(s)