Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Apbb2tm1Her
Name:	amyloid beta precursor protein binding family B member 2; targeted mutation 1, Joachim Herz
MGI ID:	MGI:3615374
Synonyms:	Apbb2tm1Sgnt, Fe65l1-
Gene:	Apbb2  Location: Chr5:66456046-66776127 bp, - strand  Genetic Position: Chr5, 34.43 cM
Alliance:	Apbb2tm1Her page

Germline Transmission:	Earliest citation of germline transmission: J:105160
Parent Cell Line:	SM1 (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A targeting vector was designed to replace 692 nucleotides of exon 4 with a tau-LacZ fusion protein and a neo cassette. Protein was not detected by Western blot analysis. (J:105160)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Apbb2 Mutation:	66 strains or lines available

Original:	J:105160 Guenette S, et al., Essential roles for the FE65 amyloid precursor protein-interacting proteins in brain development. EMBO J. 2006 Jan 25;25(2):420-31
All:	3 reference(s)