Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Osr1tm1Jian
Name:	odd-skipped related transcription factor 1; targeted mutation 1, Rulang Jiang
MGI ID:	MGI:3613748
Synonyms:	Odd1-, Odd1tm1Jian, Odd1tm1RJ
Gene:	Osr1  Location: Chr12:9624442-9631500 bp, + strand  Genetic Position: Chr12, 4.05 cM
Alliance:	Osr1tm1Jian page

Germline Transmission:	Earliest citation of germline transmission: J:104942
Parent Cell Line:	CJ7 (ES Cell)
Strain of Origin:	129S1/Sv-Oca2+ Tyr+ Kitl+

Allele Type:    Targeted (Null/knockout, Reporter) Mutation:    Insertion   Mutation details: A targeting construct was designed to insert a lacZ-loxP-neo-loxP cassette into exon 2. The cassette replaces 335 bp of the coding region. The expected protein would contain a functional beta-gal fused to the N-terminal 16 amino acids. X-gal staining detected lacZ activity corresponding to expected activity of the endogenous protein. (J:104942)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	145 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	18 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Osr1 Mutation:	16 strains or lines available

Original:	J:104942 Wang Q, et al., Odd-skipped related 1 (Odd 1) is an essential regulator of heart and urogenital development. Dev Biol. 2005 Dec 15;288(2):582-94
All:	13 reference(s)