Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Polqtm1Jcs
Name:	polymerase (DNA directed), theta; targeted mutation 1, John C Schimenti
MGI ID:	MGI:3610670
Synonyms:	Polq-
Gene:	Polq  Location: Chr16:36832148-36915779 bp, + strand  Genetic Position: Chr16, 26.32 cM, cytoband B4
Alliance:	Polqtm1Jcs page

Germline Transmission:	Earliest citation of germline transmission: J:94088
Parent Cell Line:	v6.4 (ES Cell)
Strain of Origin:	(C57BL/6J x 129S4/SvJae)F1

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A targeting vector was designed to insert an in-frame stop codon into exon 1 and replace exons 2-5 with a neomycin resistance gene. (J:94088)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Polq Mutation:	126 strains or lines available

Original:	J:94088 Shima N, et al., The Mouse Genomic Instability Mutation chaos1 Is an Allele of Polq That Exhibits Genetic Interaction with Atm. Mol Cell Biol. 2004 Dec;24(23):10381-9
All:	10 reference(s)