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Gene Expression Data
Assay Details
Assay
Reference: J:87397 Sumazaki R, et al., Conversion of biliary system to pancreatic tissue in Hes1-deficient mice. Nat Genet. 2004 Jan;36(1):83-7
Assay type: Immunohistochemistry
MGI Accession ID: MGI:3608961
Gene symbol: Ins2
Gene name: insulin II
Antibody: anti-insulin
Detection system: Secondary antibody coupled to horseradish peroxidase
Assay notes: Antibody specificity was not provided; both family members have been annotated.
Results
Specimen 4d: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: common bile duct Absent 4d

Specimen 4k: embryonic day 15.5; Hes1tm1Fgu/Hes1tm1Fgu (more )
Structure Level Pattern Image Note
TS23: common bile duct Present 4k In the mutant mouse the hypoplastic biliary system seems to be converted to pancreatic tissue.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/30/2025
MGI 6.24
The Jackson Laboratory