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Gene Expression Data
Assay Details
Assay
Reference: J:85655 Tonissoo T, et al., Expression of ric-8 (synembryn) gene in the nervous system of developing and adult mouse. Gene Expr Patterns. 2003 Oct;3(5):591-4
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:3608772
Gene symbol: Ric8a
Gene name: RIC8 guanine nucleotide exchange factor A
Reporter: lacZ
Direct Detection
Assay notes: Embryos were fixed in 2% paraformaldehyde and 0.2% glutaraldehyde; adults were fixed with 4% paraformaldehyde.
Results
Specimen 1A: embryonic day 9.5; Ric8atm1Aks/Ric8a+ (more )
Structure Level Pattern Image Note
TS15: facio-acoustic preganglion complex Present 1A
TS15: trigeminal preganglion Present 1A

Specimen 1B: embryonic day 10.5; Ric8atm1Aks/Ric8a+ (more )
Structure Level Pattern Image Note
TS17: acoustic ganglion Present 1B
TS17: dorsal root ganglion Present 1B
TS17: facial ganglion Present 1B
TS17: glossopharyngeal ganglion Present 1B
TS17: neural tube Present 1B
TS17: peripheral nerve trunk Present 1B
TS17: trigeminal ganglion Present 1B
TS17: vagus ganglion Present 1B

Specimen 1C: embryonic day 11.5; Ric8atm1Aks/Ric8a+ (more )
Structure Level Pattern Image Note
TS20: dorsal root ganglion Present 1C
TS20: facial ganglion Present 1C
TS20: glossopharyngeal ganglion Present 1C
TS20: hindbrain Present 1C
TS20: midbrain Present 1C
TS20: peripheral nerve trunk Present 1C
TS20: spinal cord Present 1C
TS20: trigeminal ganglion Present 1C
TS20: vagus ganglion Present 1C
TS20: vomeronasal organ Present 1C

Specimen 2A: embryonic day 12.0; Ric8atm1Aks/Ric8a+ (more )
Structure Level Pattern Image Note
TS20: diencephalon Present 2A
TS20: metencephalon Present 2A
TS20: spinal cord Present 2A

Specimen 2B: embryonic day 12.0; Ric8atm1Aks/Ric8a+ (more )
Structure Level Pattern Image Note
TS20: endolymphatic sac Present 2B
TS20: hindbrain Present 2B
TS20: trigeminal ganglion Present 2B
TS20: vestibulo-cochlear ganglion Present 2B

Specimen 2C: embryonic day 12.0; Ric8atm1Aks/Ric8a+ (more )
Structure Level Pattern Image Note
TS20: vomeronasal organ Present 2C

Specimen 2D: embryonic day 12.0; Ric8atm1Aks/Ric8a+ (more )
Structure Level Pattern Image Note
TS20: facial ganglion Present 2D
TS20: lens vesicle Present 2D
TS20: optic stalk Present 2D
TS20: trigeminal ganglion Present 2D

Specimen 2E: embryonic day 12.0; Ric8atm1Aks/Ric8a+ (more )
Structure Level Pattern Image Note
TS20: spinal cord Present 2E Expression is present in dorsal and ventral part of the neural tube.
TS20: dorsal root ganglion Present 2E

Specimen 2F: embryonic day 12.0; Ric8atm1Aks/Ric8a+ (more )
Structure Level Pattern Image Note
TS20: notochord Present 2F
TS20: peripheral nerve trunk Present 2F

Specimen 3A: postnatal adult; Ric8atm1Aks/Ric8a+ (more )
Structure Level Pattern Image Note
TS28: cerebral cortex Present 3A
TS28: cingulate cortex Present 3A
TS28: telencephalon Present Regionally restricted 3A Expression is present in the ependymal cell layer of the lateral ventricle.

Specimen 3B: postnatal adult; Ric8atm1Aks/Ric8a+ (more )
Structure Level Pattern Image Note
TS28: caudate-putamen Present 3B
TS28: telencephalon Present Regionally restricted 3B Expression is present in the indusium griseum and in the ependymal cell layer of the lateral ventricle.

Specimen 3C: postnatal adult; Ric8atm1Aks/Ric8a+ (more )
Structure Level Pattern Image Note
TS28: hippocampus granule cell layer Present 3C
TS28: hippocampus pyramidal cell layer Present 3C
TS28: subiculum Present 3C

Specimen 3D: postnatal adult; Ric8atm1Aks/Ric8a+ (more )
Structure Level Pattern Image Note
TS28: cerebellum granule cell layer Present 3D

Specimen 3E: postnatal adult; Ric8atm1Aks/Ric8a+ (more )
Structure Level Pattern Image Note
TS28: brain Present Regionally restricted 3E Expression is present in the ependymal layer around the aqueduct of Sylvius.

Specimen 3F: postnatal adult; Ric8atm1Aks/Ric8a+ (more )
Structure Level Pattern Image Note
TS28: hippocampus granule cell layer Present 3F
TS28: hippocampus pyramidal cell layer Present 3F
TS28: subiculum Present 3F

Specimen 3G: postnatal adult; Ric8atm1Aks/Ric8a+ (more )
Structure Level Pattern Image Note
TS28: cerebellum granule cell layer Present 3G

Specimen 3H: postnatal adult; Ric8atm1Aks/Ric8a+ (more )
Structure Level Pattern Image Note
TS28: pineal gland Present 3H

Specimen 3I: postnatal adult; Ric8atm1Aks/Ric8a+ (more )
Structure Level Pattern Image Note
TS28: caudate-putamen Present 3I


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory