Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Prdm1tm1Clme
Name:	PR domain containing 1, with ZNF domain; targeted mutation 1, Kathryn Calame
MGI ID:	MGI:3605621
Synonyms:	Blimp-1flox, Prdm1CA, Prdm1flox
Gene:	Prdm1  Location: Chr10:44313173-44404497 bp, - strand  Genetic Position: Chr10, 23.24 cM
Alliance:	Prdm1tm1Clme page

Germline Transmission:	Earliest citation of germline transmission: J:101890
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: LoxP sites were inserted to flank exons 6-8, encompassing sequence that encodes the zinc finger motifs. (J:101890)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	4 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	4 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Prdm1 Mutation:	64 strains or lines available

Original:	J:101890 Shapiro-Shelef M, et al., Blimp-1 is required for the formation of immunoglobulin secreting plasma cells and pre-plasma memory B cells. Immunity. 2003 Oct;19(4):607-20
All:	111 reference(s)