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Gene Expression Data
Assay Details
Assay
Reference: J:83132 Settle SH Jr, et al., Multiple joint and skeletal patterning defects caused by single and double mutations in the mouse Gdf6 and Gdf5 genes. Dev Biol. 2003 Feb 1;254(1):116-30
Assay type: RNA in situ
MGI Accession ID: MGI:3605539
Gene symbol: Gdf6
Gene name: growth differentiation factor 6
Probe: Gdf6 cDNA1
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 1B: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: forelimb Present Regionally restricted 1B Expression is in the joints of the wrist.
TS21: elbow joint primordium Present 1B
TS21: hand Present Regionally restricted 1B Expression is in the perimeter of the digit ray, absent in interphalangeal and metacarpophalangeal joints.
TS21: shoulder joint primordium Absent 1B

Specimen 1D: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: hindlimb Present Regionally restricted 1D Expression is in the joints of the ankle.

Specimen Not Shown: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: knee joint primordium Present Regionally restricted

Specimen Not Shown: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: forelimb digit Present Regionally restricted Expression is in the last interphalangeal joint.
TS23: forelimb digit 1 Present Regionally restricted Expression is around the tip.

Specimen 4E: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: incus Present Regionally restricted 4E Expression is in stripes at the articular surfaces between the malleus and incus, the incus and stapes, and the stapes and oval window.
TS25: malleus Present Regionally restricted 4E Expression is in stripes at the articular surfaces between the malleus and incus, the incus and stapes, and the stapes and oval window.
TS25: stapes Present Regionally restricted 4E Expression is in stripes at the articular surfaces between the malleus and incus, the incus and stapes, and the stapes and oval window.

Specimen 4F: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: incus Present Regionally restricted 4F Expression is in stripes at the articular surfaces between the malleus and incus, the incus and stapes, and the stapes and oval window.
TS26: malleus Present Regionally restricted 4F Expression is in stripes at the articular surfaces between the malleus and incus, the incus and stapes, and the stapes and oval window.
TS26: stapes Present Regionally restricted 4F Expression is in stripes at the articular surfaces between the malleus and incus, the incus and stapes, and the stapes and oval window.

Specimen 5E: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: vault of skull Present Regionally restricted 5E Expression is in the sutures.

Specimen 7I: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: vertebra Present Regionally restricted 7I Expression is in stripes corresponding to the forming joints between the vertebrae.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory