Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Foxe3tm1Mjam
Name:	forkhead box E3; targeted mutation 1, Milan Jamrich
MGI ID:	MGI:3604211
Synonyms:	Foxe3-
Gene:	Foxe3  Location: Chr4:114782344-114783210 bp, - strand  Genetic Position: Chr4, 52.73 cM, cytoband C7
Alliance:	Foxe3tm1Mjam page

Germline Transmission:	Earliest citation of germline transmission: J:101355
Parent Cell Line:	AB1 (ES Cell)
Strain of Origin:	129S7/SvEvBrd-Hprt1+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A PGK-loxP-neo-containing cassette replaced the entire coding region of the locus. In situ hybridization showed that developing lenses of mutants lacked mRNA. (J:101355)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

15 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Foxe3 Mutation:	15 strains or lines available

Original:	J:101355 Medina-Martinez O, et al., Severe defects in proliferation and differentiation of lens cells in Foxe3 null mice. Mol Cell Biol. 2005 Oct;25(20):8854-63
All:	3 reference(s)