Tg(Eno2-APPSwe)1228Ykk
Transgene Detail
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| Symbol: |
Tg(Eno2-APPSwe)1228Ykk |
| Name: |
transgene insertion 1228, Yong K Kim |
| MGI ID: |
MGI:3603945 |
| Synonyms: |
Am1228 |
| Transgene: |
Tg(Eno2-APPSwe)1228Ykk Location: unknown
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| Alliance: |
Tg(Eno2-APPSwe)1228Ykk page
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| Transgene Type: |
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Transgenic (Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(Eno2-APPSwe)1228Ykk expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Homolog in Mouse |
Note |
| human |
APP (351) |
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Mutation details: The neuron specific rat enolase 2 promoter was used to drive expression of the amyloid protein precursor bearing the Swedish mutation (K670N/M671L). In this line, the level of the 42-amino acid form of the protein was higher than in control mice.
(J:100955)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:100955 Hwang DY, et al., Aberrant expressions of pathogenic phenotype in Alzheimer's diseased transgenic mice carrying NSE-controlled APPsw. Exp Neurol. 2004 Mar;186(1):20-32 |
| All: |
1 reference(s) |
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Analysis Tools
