Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Mapttm2Arbr
Name:	microtubule-associated protein tau; targeted mutation 2, Silvia Arber
MGI ID:	MGI:3590682
Synonyms:	Tauf(mGFP), Tau-GFP-nlsLacZ, Tau-loxp-STOP-lox-mGFP-IRES-NLS-LacZ, TauloxP-stop-loxP-MARCKSeGFP-IRES-nlslacZ, Taulox-STOP-lox-FLP-INLA, TauLox-STOP-Lox-mGFP-IRESnlsLacZ, TauLSL-mEGFP, Tau:lxp-stp-lxp:mGFP-inLZ, Tau-mEGFP-LacZ, TaumGFP, TaumGFP-INLA, TaumGFP_nlacZ, TaumGFP-nlacZ, Tau-nLacZ, TauR
Gene:	Mapt  Location: Chr11:104122216-104222916 bp, + strand  Genetic Position: Chr11, 67.79 cM, cytoband E1
Alliance:	Mapttm2Arbr page

Germline Transmission:	Earliest citation of germline transmission: J:100886
Parent Cell Line:	E14 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Conditional ready, Reporter) Mutation:    Insertion   Mutation details: A cassette containing loxP-STOP-loxP-mGFP-IRES-NLS-lacZ-pA was inserted into exon 2 of the locus. mGFP consists of the first 40 amino acids of the protein MARCKS, a plasmalemmal targeting sequence, fused to enhanced GFP (eGFP). (J:100886, J:154023)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	4 assay results
In Structures Affected by this Mutation:	3 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Mapt Mutation:	428 strains or lines available

Original:	J:100886 Hippenmeyer S, et al., A developmental switch in the response of DRG neurons to ETS transcription factor signaling. PLoS Biol. 2005 May;3(5):e159
All:	130 reference(s)