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Gene Expression Data
Assay Details
Assay
Reference: J:44900 Belo JA, et al., Cerberus-like is a secreted factor with neutralizing activity expressed in the anterior primitive endoderm of the mouse gastrula. Mech Dev. 1997 Nov;68(1-2):45-57
Assay type: RNA in situ
MGI Accession ID: MGI:3590673
Gene symbol: Cer1
Gene name: cerberus 1, DAN family BMP antagonist
Probe: Cerr1 probe1
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 2A: embryonic day 5.5 (more )
Note: This embryo is at prestreak stage.
Structure Level Pattern Image Note
TS9: extraembryonic visceral endoderm Present Regionally restricted 2A Expression is present in the primitive endoderm on one side, including the distal tip.

Specimen 2A inset: embryonic day 5.5 (more )
Note: This embryo is at prestreak stage.
Structure Level Pattern Image Note
TS9: extraembryonic visceral endoderm Present 2A inset

Specimen 2B: embryonic day 6.5 (more )
Note: This embryo is at early streak stage.
Structure Level Pattern Image Note
TS10: extraembryonic visceral endoderm Present Regionally restricted 2B Expression is still present on one side of the embryo, but it no longer extends to the distal tip.

Specimen 2C: embryonic day 6.5 (more )
Note: This embryo is at early streak stage.
Structure Level Pattern Image Note
TS10: extraembryonic visceral endoderm Present 2C Expression is present in anterior primitive endoderm cells, on the opposite side of the primitive streak.

Specimen 2D: embryonic day 7.0 (more )
Note: This embryo is at mid-streak stage.
Structure Level Pattern Image Note
TS10: extraembryonic visceral endoderm Present Regionally restricted 2D Expression is present in the anterior primitive endoderm.

Specimen 2E: embryonic day 7.25 (more )
Note: This embryo is at late streak stage.
Structure Level Pattern Image Note
TS10: extraembryonic visceral endoderm Present Regionally restricted 2E Expression is present in the anterior primitive endoderm
TS10: definitive endoderm Present Regionally restricted 2E Expression is present in a population of endodermal cells close to the node at the tip of the embryo believed to be the precursors to the definitive endoderm.

Specimen 2F: embryonic day 7.25 (more )
Note: This embryo is at late streak stage. This is a proximal section.
Structure Level Pattern Image Note
TS10: extraembryonic visceral endoderm Present Regionally restricted 2F Expression is present in one small patch of the anterior primitive endoderm, extending laterally around approximately one-quarter of the circumference of the embryo.

Specimen 2G: embryonic day 7.25 (more )
Note: This embryo is at late streak stage. This section is from the anterior half of the embryo.
Structure Level Pattern Image Note
TS10: extraembryonic visceral endoderm Present 2G

Specimen 2H: embryonic day 7.25 (more )
Note: This embryo is at late streak stage. This section is from close to the tip of the embryo.
Structure Level Pattern Image Note
TS10: extraembryonic visceral endoderm Present 2H Expression extends laterally around three-quarters of the circumference of the embryo.
TS10: definitive endoderm Present Regionally restricted 2H Expression is present in a population of endodermal cells close to the node at the tip of the embryo believed to be the precursors to the definitive endoderm.

Specimen 2I: embryonic day 7.5 (more )
Note: This embryo is at neural plate stage.
Structure Level Pattern Image Note
TS11: extraembryonic visceral endoderm Present Regionally restricted 2I Expression is present in the anterior third of the embryo, underlying the prospective anterior neuroectoderm.
TS11: definitive endoderm Present 2I
TS11: node Absent 2I

Specimen 2J: embryonic day 7.75 (more )
Note: This embryo is at early head fold stage.
Structure Level Pattern Image Note
TS11: extraembryonic visceral endoderm Present Regionally restricted 2J Expression weakens in lateral regions of the anterior endoderm and perdures in the midline.

Specimen 2K: embryonic day 8.0 (more )
Note: This embryo is at late head fold stage. This is a transverse section.
Structure Level Pattern Image Note
TS12: embryo endoderm Present 2K Expression is present in all cells of the midline from the rostral end of the embryo to proximal to the node, including anterior gut endoderm and mesoderm from the prechordal and notochordal plates.
TS12: embryo mesenchyme Present 2K Expression is present in all cells of the midline from the rostral end of the embryo to proximal to the node, including anterior gut endoderm and mesoderm from the prechordal and notochordal plates.
TS12: notochordal plate Present 2K Expression is present in all cells of the midline from the rostral end of the embryo to proximal to the node, including anterior gut endoderm and mesoderm from the prechordal and notochordal plates.

Specimen 3A: embryonic day 7.5 (more )
Structure Level Pattern Image Note
TS11: embryo mesoderm Present Regionally restricted 3A Expression is present in the most rostral portion of the somitic mesoderm.

Specimen 3B: embryonic day 7.5 (more )
Note: This section is from the embryo pictured in 3A.
Structure Level Pattern Image Note
TS11: embryo mesoderm Present Regionally restricted 3B Expression is present in the mesoderm of the forming somites and adjoining presomitic mesoderm.

Specimen 3C: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: trunk somite Present Regionally restricted 3C Expression is restricted to the last two somites formed.
TS13: trunk unsegmented mesenchyme Present 3C Expression is present in most rostral portion of the presomitic mesoderm.

Specimen 3D: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: tail somite Present Regionally restricted 3D Expression is restricted to the last two somites formed.
TS19: tail unsegmented mesenchyme Present Regionally restricted 3D Expression is present in presomitic mesoderm.


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory