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Gene Expression Data
Assay Details
Assay
Reference: J:90043 Acosta L, et al., Regional expression of L-type calcium channel subunits during cardiac development. Dev Dyn. 2004 May;230(1):131-6
Assay type: Immunohistochemistry
MGI Accession ID: MGI:3590320
Gene symbol: Cacnb4
Gene name: calcium channel, voltage-dependent, beta 4 subunit
Antibody: anti-beta4 subunit
Detection system: Secondary antibody coupled to alkaline phosphatase
Results
Specimen 2d: postnatal adult (more )
Structure Level Pattern Image Note
TS28: heart Present Uniform 2d Homogeneous expression in the myocardium.
TS28: aorta Absent 2d Absent in smooth muscle cells.
TS28: pulmonary artery Absent 2d Absent in smooth muscle cells.

Specimen Not Shown: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: cardiac muscle tissue Weak

Specimen 4c: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: common atrial chamber cardiac muscle Present 4c
TS17: primitive ventricle cardiac muscle Present 4c
TS17: atrioventricular canal Weak 4c
TS17: outflow tract Weak 4c
TS17: heart Present Regionally restricted 4c Absent in atrioventricular cushions.

Specimen 4f: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: cardiac muscle tissue Present 4f

Specimen 4i,l: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: cardiac muscle tissue Present 4i , 4l
TS20: atrioventricular canal Weak 4i , 4l

Specimen 5b,d: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: atrium cardiac muscle Present Uniform 5b , 5d
TS23: ventricle cardiac muscle Present Uniform 5b , 5d
TS23: heart Weak Regionally restricted 5b , 5d Expression is weak in the ventricular conduction system.

Specimen 5f: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: atrium cardiac muscle Present Uniform 5f
TS23: ventricle cardiac muscle Present Uniform 5f
TS23: heart Weak Regionally restricted 5f Expression is reduced in the atrioventricular node and the bundle of His.

Specimen 5h: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: heart Present Uniform 5h


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory