Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Ccdc62repro29
Name:	coiled-coil domain containing 62; reproductive mutant 29, JAX Reproductive Mutagenisis Program
MGI ID:	MGI:3590192
Synonyms:	G1-485-3
Gene:	Ccdc62  Location: Chr5:124068683-124107958 bp, + strand  Genetic Position: Chr5, 63.28 cM
Alliance:	Ccdc62repro29 page

Strain of Origin:

C57BL/6J

Allele Type:    Chemically induced (ENU) (Not Specified) Mutation:    Single point mutation   Mutation details: ENU mutagenesis created a C>T point mutation in exon 6, changing arginine codon CGA to stop codon TGA (p.Arg284Stop or p.R284*) in the highly conserved second coiled-coil domain. Western blot analysis showed the expression of a truncated peptide from this allele and qRT-PCR showed a significant reduction of mRNA expression from the allele in testes. (J:244081) Inheritance:    Recessive

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ccdc62 Mutation:	16 strains or lines available

Original:	J:92463 JAX Reproductive Mutagenesis Program, Heritable mouse mutants from The Jackson Laboratory Reproductive Genomics Mutagenesis Program. MGI Direct Data Submission. 2004-7;
All:	2 reference(s)