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Gene Expression Data
Assay Details
Assay
Reference: J:89196 Hormi-Carver KK, et al., Protein phosphatase 1alpha is required for murine lung growth and morphogenesis. Dev Dyn. 2004 May;229(4):791-801
Assay type: Immunohistochemistry
MGI Accession ID: MGI:3589927
Gene symbol: Ppp1ca
Gene name: protein phosphatase 1 catalytic subunit alpha
Antibody: PP1alpha antibody
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 2A: postnatal adult (more )
Structure Level Pattern Image Note
TS28: lung Present 2A
Specimen 2B: postnatal adult (more )
Structure Level Pattern Image Note
TS28: lung Present 2B
Specimen 2C: postnatal adult (more )
Structure Level Pattern Image Note
TS28: lung Present 2C
Specimen 2D: postnatal adult (more )
Structure Level Pattern Image Note
TS28: lung Present 2D
Specimen 3A: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: lung Present 3A
Specimen 4A: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: lung epithelium Present 4A
TS16: lung mesenchyme Present 4A
TS16: esophagus Present 4A
TS16: trachea Present 4A
Specimen 4B: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: lung epithelium Present Regionally restricted 4B Expression is in the distal part of the airway epithelium, not in the proximal part.
TS24: lung mesenchyme Present Regionally restricted 4B Expression is in surrounding mesenchyme of all small bronchioles.
Specimen 4C: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: lung epithelium Strong Regionally restricted 4C Protein was found in Clara cells and around the alveolar sacs.
TS26: lung mesenchyme Trace 4C
Specimen 4D: embryonic day 19.0 (more )
Structure Level Pattern Image Note
TS26: lung epithelium Very strong 4D Expression is in saccular, bronchial, and bronchiolar epithelial cells.
Specimen 4E: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: lung Very strong Regionally restricted 4E Expression is in saccular, bronchial, and bronchiolar epithelial cells.
Specimen 4F: postnatal adult (more )
Structure Level Pattern Image Note
TS28: lung Present Regionally restricted 4F Expression is in saccular, bronchial, and bronchiolar epithelial cells.
Specimen 5A: embryonic day 18.0 (more )
Note: Double labeled: blue - Ppp1ca; brown - beta-tubulin IV.
Structure Level Pattern Image Note
TS26: lung epithelium Present 5A
Specimen 5C: postnatal adult (more )
Note: Double labeled: blue - Ppp1ca; brown - beta-tubulin IV.
Structure Level Pattern Image Note
TS28: lung Present 5C Expression is in ciliated epithelial cells.
Specimen 6A: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: trachea epithelium Present 6A
TS16: trachea mesenchyme Present 6A
Specimen 6B: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: esophagus epithelium Present 6B
TS16: esophagus mesenchyme Present 6B
Specimen 6C: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: trachea epithelium Strong 6C
TS24: trachea cartilaginous ring Weak 6C
TS24: trachea mesenchyme Weak 6C
Specimen 6D: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: esophagus epithelium Strong 6D
TS24: esophagus mesenchyme Weak 6D
Specimen 6E: postnatal day 6 (more )
Structure Level Pattern Image Note
TS28: trachea Very strong Regionally restricted 6E Expression is in the surface epithelium and multiple submucosal glands.
Specimen 6F: postnatal day 6 (more )
Structure Level Pattern Image Note
TS28: esophagus Very strong Regionally restricted 6F Expression is in the monolayer epithelium of the esophagus.
Specimen Not Shown: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: lung epithelium Present
TS18: lung mesenchyme Present
TS18: trachea epithelium Present
TS18: trachea mesenchyme Present
Specimen Not Shown: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: lung epithelium Present
TS21: lung mesenchyme Present
TS21: trachea epithelium Present
TS21: trachea mesenchyme Present
Specimen Not Shown: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: lung epithelium Present
TS22: trachea epithelium Present
TS22: trachea mesenchyme Weak
TS22: lung mesenchyme Present Regionally restricted Expression is in surrounding mesenchyme of all small bronchioles.
Specimen Not Shown: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: lung epithelium Present
TS23: trachea epithelium Present
TS23: trachea mesenchyme Weak
TS23: lung mesenchyme Present Regionally restricted Expression is in surrounding mesenchyme of all small bronchioles.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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