Gene Expression Data
Assay Details
Assay
|
Reference:
|
J:96550
Williams TM, et al., Candidate downstream regulated genes of HOX group 13 transcription factors with and without monomeric DNA binding capability. Dev Biol. 2005 Mar 15;279(2):462-80
|
Assay type:
|
RNA in situ
|
MGI Accession ID:
|
MGI:3588178
|
Gene symbol:
|
Igfbp4
|
Gene name:
|
insulin-like growth factor binding protein 4
|
Probe:
|
Igfbp4 cDNA5
|
Probe preparation:
|
Antisense labelled with digoxigenin RNA
|
Visualized with:
|
Alkaline phosphatase
|
|
Results
|
Specimen
4L:
embryonic day 12.5
(more )
Specimen
4L:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 12.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Specimen
5A:
embryonic day 12.5
(more )
Note: Stage 7 limb bud.
Specimen
5A:
(close )
Genetic Background:
|
involves: 129S2/SvPas * C57BL/6J
|
Age:
|
embryonic day 12.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Note:
|
Stage 7 limb bud.
|
Structure |
Level |
Pattern |
Image |
Note |
TS20: hand |
Strong |
Regionally restricted |
5A
|
Strong expression in proximal forelimb bud with weaker expression throughout the distal autopod.
|
Specimen
5B:
embryonic day 12.5
(more )
Note: Stage 8 limb bud.
Specimen
5B:
(close )
Genetic Background:
|
involves: 129S2/SvPas * C57BL/6J
|
Age:
|
embryonic day 12.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Note:
|
Stage 8 limb bud.
|
Specimen
5C:
embryonic day 12.5
(more )
Note: Stage 9 limb bud.
Specimen
5C:
(close )
Genetic Background:
|
involves: 129S2/SvPas * C57BL/6J
|
Age:
|
embryonic day 12.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Note:
|
Stage 9 limb bud.
|
Specimen
5D:
(close )
Genetic Background:
|
involves: 129S2/SvPas * C57BL/6J
|
Mutant Allele(s):
|
Hoxa13tm2Ipc/Hoxa13tm2Ipc
|
Age:
|
embryonic day 12.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Note:
|
Stage 7 limb bud.
|
Structure |
Level |
Pattern |
Image |
Note |
TS20: hand |
Strong |
Regionally restricted |
5D
|
Strong expression in proximal forelimb bud with weaker expression throughout the distal autopod as in wild type.
|
Specimen
5E:
(close )
Genetic Background:
|
involves: 129S2/SvPas * C57BL/6J
|
Mutant Allele(s):
|
Hoxa13tm2Ipc/Hoxa13tm2Ipc
|
Age:
|
embryonic day 12.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Note:
|
Stage 8 limb bud.
|
Structure |
Level |
Pattern |
Image |
Note |
TS20: hand |
Present |
Regionally restricted |
5E
|
Expression is detected in the proximal forelimb bud with weaker expression in the interdigital regions.
|
TS20: forelimb interdigital region |
Weak |
Regionally restricted |
5E
|
Expression in the mutant interdigital regions appears much weaker compared to wild type.
|
Specimen
5F:
(close )
Genetic Background:
|
involves: 129S2/SvPas * C57BL/6J
|
Mutant Allele(s):
|
Hoxa13tm2Ipc/Hoxa13tm2Ipc
|
Age:
|
embryonic day 12.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Note:
|
Stage 9 limb bud.
|
|