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Sall4Gt(XE027)Byg
Gene trapped Allele Detail
Summary
Symbol: Sall4Gt(XE027)Byg
Name: spalt like transcription factor 4; gene trap XE027, BayGenomics
MGI ID: MGI:3587949
Synonyms: Sall4-1a,b, Sall4GT, Sall4Gt(pGT1Lxf)1Ucd
Gene: Sall4  Location: Chr2:168590252-168609121 bp, - strand  Genetic Position: Chr2, 88.99 cM
Alliance: Sall4Gt(XE027)Byg page
Mutation
origin
Mutant Cell Line:  XE027
Germline Transmission:  Earliest citation of germline transmission: J:105332
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Gene trapped (Reporter)
Mutation:    Insertion of gene trap vector     Vector: pGT1Lxf     Vector Type: gene trap
 
Mutation detailsAn insertion into exon 2 is predicted to result in a fusion protein between the endogenous protein after amino acid residue 383 and the betageo protein. (J:105332)
Sequence Tags: 
Sequence tag details (1 tag)
Genome Context: 
Genome Browser view of this mutation
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 7 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Sall4 Mutation:  144 strains or lines available
Notes
All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.
References
Original:  J:105332 Koshiba-Takeuchi K, et al., Cooperative and antagonistic interactions between Sall4 and Tbx5 pattern the mouse limb and heart. Nat Genet. 2006 Feb;38(2):175-183
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory