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Nmt1Gt(XE400)Byg
Gene trapped Allele Detail
Summary
Symbol: Nmt1Gt(XE400)Byg
Name: N-myristoyltransferase 1; gene trap XE400, BayGenomics
MGI ID: MGI:3586313
Synonyms: Nmt1-, Nmt1Gt(pGT1lxf)1Sgy
Gene: Nmt1  Location: Chr11:102919163-102959734 bp, + strand  Genetic Position: Chr11, 66.71 cM, cytoband D
Alliance: Nmt1Gt(XE400)Byg page
Mutation
origin
Mutant Cell Line:  XE400
Germline Transmission:  Earliest citation of germline transmission: J:99794
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Gene trapped (Null/knockout, Reporter)
Mutation:    Insertion of gene trap vector     Vector: pGT1Lxf     Vector Type: gene trap
 
Mutation detailsA gene trap vector, pGT1Lxt, designed to create an in-frame fusion between the 5' exons of the locus and betagalactosidase and neomycin resistance genes was inserted into intron 3. Northern blot confirmed the insertion of the vector and the presence of a fusion transcript. (J:99932)
Sequence Tags: 
Sequence tag details (1 tag)
Genome Context: 
Genome Browser view of this mutation
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 13 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nmt1 Mutation:  52 strains or lines available
Notes
All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.
References
Original:  J:99932 Yang SH, et al., N-myristoyltransferase 1 is essential in early mouse development. J Biol Chem. 2005 May 13;280(19):18990-5
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory