Mknk2 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:93300 Blackshaw S, et al., Genomic analysis of mouse retinal development. PLoS Biol. 2004 Oct;2(9):E247
Assay type:	RNA in situ
MGI Accession ID:	MGI:3586064
Gene symbol:	Mknk2
Gene name:	MAP kinase-interacting serine/threonine kinase 2

Probe:	IMAGE clone 762979
Probe preparation:	Antisense labelled with digoxigenin RNA
Visualized with:	Alkaline phosphatase
Assay notes:	This data is from Supplemental Table 5, Gene column, row: 42126 MAP kinase-interacting serine/threonine kinase 2. After cryosectioning, tissue was fixed for 10' in 4% paraformaldehyde prior to processing.

Results

Specimen E14: embryonic day 14.0 (more

)

Structure	Level	Pattern	Image	Note
TS22: neural retinal epithelium	Present	Regionally restricted		Expression was detected in the inner neuroblastic layer.

Submitted Image - mnk2E16.5 ©

Specimen E16: embryonic day 16.0 (more

)

Structure	Level	Pattern	Image	Note
TS24: retina nuclear layer	Present	Regionally restricted	Submitted Image - mnk2E16.5	Expression was detected in the inner neuroblastic layer.

Submitted Image - mnk2E18.5 ©

Specimen E18: embryonic day 18.0 (more

)

Structure	Level	Pattern	Image	Note
TS26: retina inner nuclear layer	Present		Submitted Image - mnk2E18.5	Expression was detected in the inner neuroblastic layer.

Submitted Image - mnk2P0.5 ©

Submitted Image - mnk2P1.5 ©

Specimen P0/1: postnatal day 0-1 (more

)

Structure	Level	Pattern	Image	Note
TS27: retina inner nuclear layer	Present		Submitted Image - mnk2P1.5 , Submitted Image - mnk2P0.5	Expression was detected in the inner neuroblastic layer.

Submitted Image - mnk2P2.5 ©

Submitted Image - mnk2P3.5 ©

Specimen P2/3: postnatal day 2-3 (more

)

Structure	Level	Pattern	Image	Note
TS27: retina inner nuclear layer	Present		Submitted Image - mnk2P2.5 , Submitted Image - mnk2P3.5	Expression was detected in the inner neuroblastic layer.
TS27: retina outer nuclear layer	Present	Regionally restricted	Submitted Image - mnk2P2.5 , Submitted Image - mnk2P3.5	Expression was detected in the vitreal outer neuroblastic layer.

Submitted Image - mnk2P4.5 ©

Submitted Image - mnk2P5.5 ©

Specimen P4/5: postnatal day 4-5 (more

)

Structure	Level	Pattern	Image	Note
TS28: retina inner nuclear layer	Present		Submitted Image - mnk2P4.5 , Submitted Image - mnk2P5.5	Expression was detected in the inner neuroblastic layer.
TS28: retina outer nuclear layer	Present	Regionally restricted	Submitted Image - mnk2P4.5 , Submitted Image - mnk2P5.5	Expression was detected in the vitreal outer neuroblastic layer.

Submitted Image - mnk2P6.5 ©

Submitted Image - mnk2P7.5 ©

Specimen P6/7: postnatal day 6-7 (more

)

Structure	Level	Pattern	Image	Note
TS28: retina layer	Present	Regionally restricted	Submitted Image - mnk2P6.5 , Submitted Image - mnk2P7.5	Expression was detected in amacrine cells.
TS28: retina ganglion cell layer	Present		Submitted Image - mnk2P7.5 , Submitted Image - mnk2P6.5
TS28: retina inner nuclear layer	Present		Submitted Image - mnk2P7.5 , Submitted Image - mnk2P6.5

Specimen P8/10: postnatal day 8-10 (more

)

Structure	Level	Pattern	Image	Note
TS28: retina layer	Present	Regionally restricted	Submitted Image - mnk2P10.5 , Submitted Image - mnk2P8.5 , Submitted Image - mnk2P9.5	Expression was detected in amacrine cells.
TS28: retina ganglion cell layer	Present		Submitted Image - mnk2P8.5 , Submitted Image - mnk2P10.5 , Submitted Image - mnk2P9.5
TS28: retina inner nuclear layer	Present		Submitted Image - mnk2P10.5 , Submitted Image - mnk2P8.5 , Submitted Image - mnk2P9.5

Specimen Adult: postnatal adult (more

)

Structure	Level	Pattern	Image	Note
TS28: retina layer	Present	Regionally restricted	Submitted Image - mnk2Adult	Expression was detected in amacrine cells.

Specimen CNS: postnatal day 6 (more

)

Structure	Level	Pattern	Image	Note
TS28: central nervous system	Present	Regionally restricted		Expression was detected in a subset (widespread).

Specimen Embryo: embryonic day 16.0 (more

)

Structure	Level	Pattern	Note
TS24: salivary gland	Present
TS24: embryo mesenchyme	Present	Regionally restricted	Expression was detected in fat.
TS24: embryo	Present		Expression was widespread.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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