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Gene Expression Data
Assay Details
Assay
Reference: J:93300 Blackshaw S, et al., Genomic analysis of mouse retinal development. PLoS Biol. 2004 Oct;2(9):E247
Assay type: RNA in situ
MGI Accession ID: MGI:3585404
Gene symbol: Six3os1
Gene name: SIX homeobox 3, opposite strand 1
Probe: IMAGE clone 2101617
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Assay notes: This data is from Supplemental Table 5, Gene column, row: 150838 ESTs/15kb 5' of Six3. After cryosectioning, tissue was fixed for 10' in 4% paraformaldehyde prior to processing.
Results
Specimen E14: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: neural retinal epithelium Present Regionally restricted Submitted Image - T25e14short , 6_RNCR1 E14 , Submitted Image - T25e14 , Submitted Image - T25e14 , Submitted Image - T25e14shortb Expression was detected in the outer neuroblastic layer and in a subset of cells in the inner neuroblastic layer. The expression level was higher in the outer neuroblastic layer.
Specimen E16: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: retina nuclear layer Present Regionally restricted Submitted Image - T25e16 , Submitted Image - T25e16 , Submitted Image - T25e16short , 6_RNCR1 E16 , Submitted Image - T25e16short2 , Submitted Image - T25e16b Expression was detected in the outer neuroblastic layer and a subset of cells in the inner neuroblastic layer. The expression level was higher in the outer neuroblastic layer.
Specimen E18: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: retina outer nuclear layer Present Submitted Image - T25e18 , 6_RNCR1 E18 , Submitted Image - T25e18 Expression was detected in the outer neuroblastic layer.
TS26: retina inner nuclear layer Present Regionally restricted Submitted Image - T25e18 , Submitted Image - T25e18 , 6_RNCR1 E18 Expression was detected in a subset of cells in the inner neuroblastic layer.
Specimen P0/1: postnatal day 0-1 (more )
Structure Level Pattern Image Note
TS27: retina outer nuclear layer Present Submitted Image - T25p0 , 6_RNCR1 P0 , Submitted Image - T25p0 Expression was detected in the outer neuroblastic layer.
TS27: retina inner nuclear layer Present Regionally restricted Submitted Image - T25p0 , 6_RNCR1 P0 , Submitted Image - T25p0 Expression was detected in a subset of cells in the inner neuroblastic layer.
Specimen P2/3: postnatal day 2-3 (more )
Structure Level Pattern Image Note
TS27: retina outer nuclear layer Present 6_RNCR1 P2 , Submitted Image - T25p2 , Submitted Image - T25p2 Expression was detected in the outer neuroblastic layer but was higher in the vitreal outer neuroblastic layer.
TS27: retina inner nuclear layer Present Regionally restricted Submitted Image - T25p2 , 6_RNCR1 P2 , Submitted Image - T25p2 Expression was detected in a subset of cells in the inner neuroblastic layer.
Specimen P4/5: postnatal day 4-5 (more )
Structure Level Pattern Image Note
TS28: retina outer nuclear layer Present Submitted Image - T25p4 , 6_RNCR1 P4 , Submitted Image - T25p4 Expression was detected in the outer neuroblastic layer but was higher in the vitreal outer neuroblastic layer.
TS28: retina inner nuclear layer Present Regionally restricted 6_RNCR1 P4 , Submitted Image - T25p4 , Submitted Image - T25p4 Expression was detected in a subset of cells in the inner neuroblastic layer.
Specimen P6/7: postnatal day 6-7 (more )
Structure Level Pattern Image Note
TS28: retina outer nuclear layer Present Submitted Image - T25p6 , Submitted Image - T25p6 , 6_RNCR1 P6
TS28: retina inner nuclear layer Present Submitted Image - T25p6 , Submitted Image - T25p6 , 6_RNCR1 P6
TS28: retina Present Regionally restricted 6_RNCR1 P6 , Submitted Image - T25p6 , Submitted Image - T25p6 Expression was detected in the Muller glia.
Specimen P8/10: postnatal day 8-10 (more )
Structure Level Pattern Image Note
TS28: retina outer nuclear layer Present Submitted Image - T25p8 , Submitted Image - T25p8 , 6_RNCR1 P8
TS28: retina inner nuclear layer Present Submitted Image - T25p8 , 6_RNCR1 P8 , Submitted Image - T25p8
TS28: retina Present Regionally restricted Submitted Image - T25p8 , 6_RNCR1 P8 , Submitted Image - T25p8 Expression was detected in the Muller glia.
Specimen Adult: postnatal adult (more )
Structure Level Pattern Image Note
TS28: retina Present Regionally restricted Expression was detected in the Muller glia.
Specimen CNS: postnatal day 6 (more )
Structure Level Pattern Image Note
TS28: central nervous system Absent
Specimen Embryo: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: forebrain Present Regionally restricted Expression was detected in the hippocampal field.
Specimen Embryo: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: central nervous system Present Regionally restricted Expression was detected in the ventral CNS.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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