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Gene Expression Data
Assay Details
Assay
Reference: J:98379 Zakin L, et al., Sirenomelia in Bmp7 and Tsg compound mutant mice: requirement for Bmp signaling in the development of ventral posterior mesoderm. Development. 2005 May;132(10):2489-99
Assay type: RNA in situ
MGI Accession ID: MGI:3582811
Gene symbol: T
Gene name: brachyury, T-box transcription factor T
Results
Specimen 6A: embryonic day 8.25 (more )
Structure Level Pattern Image Note
TS13: notochord Present 6A
TS13: primitive streak Present 6A

Specimen 6A': embryonic day 8.25; Twsg1tm1Emdr/Twsg1tm1Emdr, Bmp7tm1Rob/Bmp7tm1Rob (more )
Structure Level Pattern Image Note
TS13: notochord Present 6A' Expression was detected as in wild type.
TS13: primitive streak Present 6A' Expression was detected as in wild type.

Specimen 6D: embryonic day 8.25 (more )
Structure Level Pattern Image Note
TS13: notochord Present 6D
TS13: embryo mesenchyme Present Regionally restricted 6D Expression was detected in the ventral tailbud mesoderm close to the tip of the tail.

Specimen 6D': embryonic day 8.25; Twsg1tm1Emdr/Twsg1tm1Emdr, Bmp7tm1Rob/Bmp7tm1Rob (more )
Structure Level Pattern Image Note
TS13: notochord Present 6D' Expression was detected as in wild type.
TS13: embryo mesenchyme Weak Regionally restricted 6D' Expression was fainter in the ventral tailbud mesoderm close to the tip of the tail of the mutant.

Specimen 7G, 7G': embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: notochord Present 7G , 7G'
TS15: tail mesenchyme Present 7G , 7G' Expression was detected in tailbud mesoderm.

Specimen 7H, 7H': embryonic day 9.5; Twsg1tm1Emdr/Twsg1tm1Emdr, Bmp7tm1Rob/Bmp7tm1Rob (more )
Structure Level Pattern Image Note
TS15: notochord Present 7H' , 7H Expression was detected as in wild type.
TS15: tail mesenchyme Weak Regionally restricted 7H' , 7H Expression was decreased ventrally in mutant tailbud mesoderm.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/30/2025
MGI 6.24
The Jackson Laboratory