Gene Expression Data
Assay Details
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Assay
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Reference:
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J:64539
Hiltunen JO, et al., GDNF family receptors in the embryonic and postnatal rat heart and reduced cholinergic innervation in mice hearts lacking ret or GFRalpha2. Dev Dyn. 2000 Sep;219(1):28-39
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:3581612
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Gene symbol:
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Th
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Gene name:
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tyrosine hydroxylase
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Antibody:
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anti-TH (AB1542)
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Detection system:
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Secondary antibody
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Assay notes:
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It is possible another antibody (MGI:1342636) was used to obtain these results.
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Results
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Specimen
Wild type:
embryonic day 18.5
(more  )
Specimen
Wild type:
(close  )
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Genetic Background:
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involves: 129S6/SvEvTac * MF1
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Age:
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embryonic day 18.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: heart |
Present |
Regionally restricted |
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There is sparse noradrenergic immunoreactive innervation of the ventricular conduction system, the epicardium, and the coronary arteries.
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Specimen
Mutant:
(close )
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Genetic Background:
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involves: 129S/SvEv * MF1
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Mutant Allele(s):
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Rettm1Cos/Rettm1Cos
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Age:
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embryonic day 18.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: heart |
Present |
Regionally restricted |
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In the 6 mutants examined there was no difference between mutant and wild type; there is sparse noradrenergic immunoreactive innervation of the ventricular conduction system, the epicardium, and the coronary arteries.
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Specimen
6D:
postnatal week 14-16
(more )
Specimen
6D:
(close )
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Genetic Background:
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involves: 129/OlaHsd * 129/SvHsd * 129S1/Sv * 129X1/SvJ * C57BL/6J
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Age:
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postnatal week 14-16
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Sex:
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Male
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: heart left ventricle |
Present |
Regionally restricted |
6D
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Expression is present in the noradrenergic nerve fiber density in the left ventricle, as well as in the ventricular conduction system.
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Specimen
6E:
(close )
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Genetic Background:
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involves: 129/OlaHsd * 129/SvHsd * 129S1/Sv * 129X1/SvJ * C57BL/6J
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Mutant Allele(s):
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Gfra2tm1Msa/Gfra2tm1Msa
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Age:
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postnatal week 14-16
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Sex:
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Male
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: heart left ventricle |
Present |
Regionally restricted |
6E
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Expression is present in the noradrenergic nerve fiber density in the left ventricle, as well as in the ventricular conduction system; there is no difference between the mutants and wild type.
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Analysis Tools
