Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Plag1tm1Wjmv
Name:	pleiomorphic adenoma gene 1; targeted mutation 1, Wim J M Van de Ven
MGI ID:	MGI:3580633
Synonyms:	Plag1-
Gene:	Plag1  Location: Chr4:3900996-3938423 bp, - strand  Genetic Position: Chr4, 2.18 cM, cytoband A1
Alliance:	Plag1tm1Wjmv page

Germline Transmission:	Earliest citation of germline transmission: J:96846
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout, Reporter) Mutation:    Disruption caused by insertion of vector   Mutation details: A lacZ reporter gene fused in frame to the initiation codon and a PGK-neo selection cassette replaced the complete ORF. RT-PCR confirmed the complete absence of transcript in null mice. (J:96846)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	35 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	3 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Plag1 Mutation:	32 strains or lines available

Original:	J:96846 Hensen K, et al., Targeted disruption of the murine Plag1 proto-oncogene causes growth retardation and reduced fertility. Dev Growth Differ. 2004 Oct;46(5):459-70
All:	8 reference(s)