Antibody:	anti-LYVE-1
Detection system:	Secondary antibody coupled to horseradish peroxidase

Structure	Level	Pattern	Image	Note
TS17: cardiac muscle tissue	Weak			The authors state that some staining was observed in the myocardium and liver and that staining is absent everywhere else.
TS17: liver	Weak			The authors state that some staining was observed in the myocardium and liver and that staining is absent everywhere else.

Structure	Level	Pattern	Image	Note
TS17: cardiac muscle tissue	Present			The authors state that some staining was observed in the myocardium and liver and that staining is absent everywhere else.
TS17: liver	Present			The authors state that some staining was observed in the myocardium and liver and that staining is absent everywhere else.

Structure	Level	Pattern	Image	Note
TS18: cardinal vein	Present	Regionally restricted	1A	Expression is in the endocardium at the lateral part of the cardinal vein, just above the heart.
TS18: venous system	Present	Regionally restricted	1A	Some large veins showed partly positive staining at the locations where small veins sprout from the larger veins.

Structure	Level	Pattern	Image	Note
TS18: cardinal vein	Present		1B	The cardinal vein is almost completely positive.
TS18: venous system	Present	Regionally restricted	1B	Some large veins showed partly positive staining at the locations where small veins sprout from the larger veins.
TS18: notochord	Weak		1B

Structure	Level	Pattern	Image	Note
TS20: venous system	Present	Regionally restricted	1C	Expression in vessels adjacent to the cardinal vein, as well as vessels sprouting and budding from the cardinal vein.

Structure	Level	Pattern	Image	Note
TS20: venous system	Present	Regionally restricted	1D	Expression is present in vessels sprouting and budding from the cardinal vein.

Structure	Level	Pattern	Image	Note
TS21: cardiovascular system	Present	Regionally restricted	2A	Expression is in the jugular lymphatic sac.
TS21: external jugular vein	Absent		2A
TS21: internal jugular vein	Absent		2A

Structure	Level	Pattern	Image	Note
TS21: external jugular vein	Present		2B	Unlike in wild type, expression is present in the jugular vein.
TS21: internal jugular vein	Present		2B	Unlike in wild type, expression is present in the jugular vein.
TS21: cardiovascular system	Present	Regionally restricted	2B	Expression is present in the jugular lymphatic sac.

Structure	Level	Pattern	Image	Note
TS22: jugular lymph sac	Present		2C

Structure	Level	Pattern	Image	Note
TS22: jugular lymph sac	Present		2D	Expression levels are higher than those seen in wild type.

Structure	Level	Pattern	Image	Note
TS21: cardiovascular system	Present	Regionally restricted	2E	Expression is in the lymphatic venous membrane.
TS21: external jugular vein	Present		2E
TS21: internal jugular vein	Present		2E

Structure	Level	Pattern	Image	Note
TS21: external jugular vein	Present	Regionally restricted	2F
TS21: internal jugular vein	Present	Regionally restricted	2F
TS21: cardiovascular system	Present	Regionally restricted	2F	Expression is present in the jugular lymphatic sac.

Structure	Level	Pattern	Image	Note
TS22: jugular lymph sac	Present		2G

Structure	Level	Pattern	Image	Note
TS25: jugular lymph sac	Present		2H