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Gene Expression Data
Assay Details
Assay
Reference: J:51920 Caubit X, et al., Mouse Dac, a novel nuclear factor with homology to Drosophila dachshund shows a dynamic expression in the neural crest, the eye, the neocortex, and the limb bud. Dev Dyn. 1999 Jan;214(1):66-80
Assay type: RNA in situ
MGI Accession ID: MGI:3578230
Gene symbol: Dach1
Gene name: dachshund family transcription factor 1
Probe: Dac cDNA1
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 2A: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: mesenchyme derived from head mesoderm Present 2A
TS15: optic cup Present 2A
TS15: otocyst Present 2A
TS15: telencephalon Present 2A
TS15: trunk mesenchyme Present 2A
TS15: neural tube Present Regionally restricted 2A Expression is dorsal.
TS15: future midbrain Absent 2A

Specimen 2B: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: telencephalon Present Regionally restricted 2B Expression is in the neocortex.
TS18: head mesenchyme Present Regionally restricted 2B Expression is in the mesenchyme surrounding the eye.
TS18: retina Present Regionally restricted 2B Expression is in the neuroretina adjacent to the lens.
TS18: dorsal root ganglion Present 2B
TS18: limb Present 2B
TS18: trigeminal ganglion Present 2B
TS18: 2nd branchial arch Present Regionally restricted 2B Expression is at the boundary between arch 2 and 3.
TS18: 3rd branchial arch Present Regionally restricted 2B Expression is at the boundary between arch 2 and 3.
TS18: future spinal cord Strong Regionally restricted 2B Expression is dorsal.
TS18: hindbrain Strong Regionally restricted 2B Expression is dorsal.

Specimen 2C: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: cerebral cortex Strong 2C
TS20: limb Strong 2C
TS20: spinal cord Weak 2C
TS20: tail mesenchyme derived from neural crest Weak 2C
TS20: corpus striatum Absent 2C

Specimen 2D: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: cerebral cortex Strong 2D
TS21: genital tubercle Strong 2D
TS21: limb Strong 2D

Specimen 2E: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: cerebral cortex Strong 2E
TS21: genital tubercle Strong 2E
TS21: limb Strong 2E

Specimen 3A: embryonic day 8.25 (more )
Structure Level Pattern Image Note
TS13: optic pit Present 3A
TS13: future prosencephalon Present Regionally restricted 3A Expression is in a band of cells at the anterior rim of the prosencephalon and in the lamina terminalis.

Specimen 3B: embryonic day 8.25 (more )
Structure Level Pattern Image Note
TS13: future prosencephalon Present Regionally restricted 3B Expression is in a band of cells at the anterior rim of the prosencephalon and in the lamina terminalis.
TS13: 1st branchial arch Present 3B
TS13: 2nd branchial arch Present 3B

Specimen 3C: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: future prosencephalon Present 3C
TS13: head mesenchyme Present 3C
TS13: optic pit Present 3C
TS13: future midbrain Absent 3C
TS13: future hindbrain Absent 3C Absent in the metencephalon.

Specimen 3D: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: future prosencephalon Present 3D
TS13: head mesenchyme Present 3D
TS13: optic pit Present 3D
TS13: future midbrain Absent 3D
TS13: future hindbrain Absent 3D Absent in the metencephalon.

Specimen 3E: embryonic day 9.0-9.5 (more )
Structure Level Pattern Image Note
TS14: prosencephalon Present Regionally restricted 3E Expression is dorsal.
TS14: optic vesicle Present 3E

Specimen 3F: embryonic day 9.0-9.5 (more )
Structure Level Pattern Image Note
TS14: prosencephalon Present Regionally restricted 3F Expression is dorsal.
TS14: optic vesicle Present 3F

Specimen 3G: embryonic day 9.0-9.5 (more )
Structure Level Pattern Image Note
TS15: future forebrain Present Regionally restricted 3G Expression is in two dorsal areas separated by the midline which is absent in expression.

Specimen 3H: embryonic day 9.0-9.5 (more )
Structure Level Pattern Image Note
TS15: future forebrain Present Regionally restricted 3H Expression is in two dorsal areas separated by the midline which is absent in expression.
TS15: diencephalon lamina terminalis Weak 3H

Specimen 3I: embryonic day 8.0 (more )
Structure Level Pattern Image Note
TS12: head mesenchyme Present Regionally restricted 3I Expresion is in two lateral fields of cranial and trunk mesenchymal cells that stretch anteriorly to the margin of the foregut pouch where they split into two areas.
TS12: trunk mesenchyme Present Regionally restricted 3I Expresion is in two lateral fields of cranial and trunk mesenchymal cells that stretch anteriorly to the margin of the foregut pouch where they split into two areas.
TS12: 1st branchial arch mesenchyme Present 3I

Specimen 3J: embryonic day 8.25 (more )
Note: 5 somites.
Structure Level Pattern Image Note
TS13: neural tube Present Regionally restricted 3J Expression is dorsal.
TS13: future spinal cord neural crest Present 3J
TS13: head mesenchyme Present 3J
TS13: lateral plate mesoderm Present 3J
TS13: trunk mesenchyme Present 3J

Specimen 3K: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: future hindbrain Present 3K
TS15: future spinal cord Present Regionally restricted 3K Expression is dorsal.
TS15: future midbrain Absent 3K

Specimen 3L: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: future spinal cord Present Regionally restricted 3L Expression is dorsal.
TS15: trunk mesenchyme derived from neural crest Present 3L

Specimen 3M: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: neural tube Strong Regionally restricted 3M Expression is dorsal. Position is at the hindlimb.
TS18: migrating neural crest Present Regionally restricted 3M Expression is in migrating neural crest.

Specimen 3N: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: neural tube Strong Regionally restricted 3N Expression is dorsal.
TS18: dorsal root ganglion Strong 3N
TS18: sympathetic ganglion Strong 3N

Specimen 3O: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: genital tubercle Present Regionally restricted 3O Expression is in the mesenchyme.

Specimen 3Q: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: otocyst Present Regionally restricted 3Q Expression is in the dorsal rim.

Specimen 3R: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: head mesenchyme Present Regionally restricted 3R Expression is in the head mesenchyme surrounding the eye.
TS18: retina Present 3R
TS18: trigeminal ganglion Present 3R
TS18: 2nd branchial arch Present Regionally restricted 3R Expression is between arches 2 and 3.
TS18: 3rd branchial arch Present Regionally restricted 3R Expression is between arches 2 and 3.

Specimen 3S: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: rhombomere 3 Present Regionally restricted 3S Expression is ventral in two groups.

Specimen 4A: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: future hindbrain Present 4A
TS15: otocyst Present 4A

Specimen 4B: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: otocyst Present Regionally restricted 4B Expression is in dorsolateral areas.

Specimen 4C: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: interdigital region between forelimb digits 1 and 2 Present 4C
TS20: interdigital region between forelimb digits 2 and 3 Present 4C
TS20: forelimb digit 2 mesenchyme Absent 4C Absent in the chondral condensations.
TS20: forelimb digit 2 epithelium Absent 4C

Specimen 4D: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: genital tubercle Present Regionally restricted 4D Expression is in the mesenchyme.

Specimen 4E: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: neural tube Strong Regionally restricted 4E Expression is dorsal.
TS15: trunk mesenchyme Strong Regionally restricted 4E Expression is in the lateral mesenchyme.

Specimen 4F: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: dorsal root ganglion Strong 4F

Specimen 4G: embryonic day 9.25 (more )
Structure Level Pattern Image Note
TS15: optic vesicle Present 4G
TS15: telencephalon Present Regionally restricted 4G Expression is dorsal.

Specimen 4H: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: optic vesicle Present Regionally restricted 4H Expression is in the distal portion.
TS15: optic stalk Absent 4H

Specimen 4I: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: retina Present 4I

Specimen 4K: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: telencephalon Present Regionally restricted 4K Expression is dorsal.

Specimen 4L: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: lens placode Strong Regionally restricted 4L Expression is in the lens ectoderm.
TS15: diencephalon lamina terminalis Strong 4L

Specimen 4M: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: cerebral cortex Present 4M

Specimen 5B: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: forelimb bud Present Regionally restricted 5B Expression is in three areas of the mesenchyme. An anterior area of expression that extends from the anterior margin of the limb bud deep towards the midline, a posterior band, and a faint zone proximal to the ZPA.

Specimen 5C: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: forelimb bud Present Regionally restricted 5C Expression is in three area sof the mesenchyme. An anterior area of expression that extends from the anterior margin of the limb bud deep towards the midline, a posterior band, and a faint zone proximal to the ZPA.

Specimen 5D: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: forelimb bud Present 5D

Specimen 5E: embryonic day 11.75 (more )
Structure Level Pattern Image Note
TS19: forelimb bud Present 5E

Specimen 5F: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: forelimb digit 1 Present Regionally restricted 5F Expression is at the tip.
TS20: forelimb digit 2 Present Regionally restricted 5F Expression is at the tip.
TS20: forelimb digit 3 Present Regionally restricted 5F Expression is at the tip.
TS20: forelimb digit 4 Present Regionally restricted 5F Expression is at the tip.
TS20: forelimb digit 5 Present Regionally restricted 5F Expression is at the tip.
TS20: interdigital region between forelimb digits 1 and 2 Present 5F
TS20: interdigital region between forelimb digits 2 and 3 Present 5F
TS20: interdigital region between forelimb digits 3 and 4 Present 5F
TS20: interdigital region between forelimb digits 4 and 5 Present 5F

Specimen 5G: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: forelimb digit 1 Strong Regionally restricted 5G Expression is at the tip.
TS21: forelimb digit 2 Strong Regionally restricted 5G Expression is at the tip.
TS21: forelimb digit 3 Strong Regionally restricted 5G Expression is at the tip.
TS21: forelimb digit 4 Strong Regionally restricted 5G Expression is at the tip.
TS21: forelimb digit 5 Strong Regionally restricted 5G Expression is at the tip.

Specimen 6A: embryonic day 11.5; Rr29Hx/Rr29+ (more )
Structure Level Pattern Image Note
TS19: forelimb bud mesenchyme Present 6A
TS19: hindlimb bud mesenchyme Present 6A

Specimen 6B: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: forelimb bud Present 6B

Specimen 6C: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: hindlimb bud Present 6C

Specimen 6D: embryonic day 11.5; Gli3Xt/Gli3Xt (more )
Structure Level Pattern Image Note
TS19: forelimb bud Present 6D Expression in this mutant is the same as in wild-type embryos.

Specimen 6E: embryonic day 11.5; Gli3Xt/Gli3Xt (more )
Structure Level Pattern Image Note
TS19: hindlimb bud Present 6E Expression in this mutant is the same as in wild-type embryos.

Specimen 6F: embryonic day 11.5; Rr29Hx/Rr29+ (more )
Structure Level Pattern Image Note
TS19: forelimb bud mesenchyme Strong Regionally restricted 6F Expression is increased in the anterior mesenchyme compared to wild-type embryos.

Specimen 6G: embryonic day 11.5; Rr29Hx/Rr29+ (more )
Structure Level Pattern Image Note
TS19: hindlimb bud mesenchyme Strong Regionally restricted 6G Expression is increased in the anterior mesenchyme compared to wild-type embryos.


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory