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Gene Expression Data
Assay Details
Assay
Reference: J:96925 Fan T, et al., Lsh controls silencing of the imprinted Cdkn1c gene. Development. 2005 Feb;132(4):635-44
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:3578111
Gene symbol: Plagl1
Gene name: pleiomorphic adenoma gene-like 1
Reporter: lacZ
Direct Detection
Assay notes: Embryos were fixed in 0.2% glutaraldehyde, 1.5% formaldehyde in PBS. They were then X gal stained for 16 hours, fixed in liquid nitrogen, and sectioned.
Results
Specimen Lsh-/- maternal: embryonic day 13.5; Hellstm1Kmu/Hellstm1Kmu, Plagl1tm1Kmu/Plagl1+ (more )
Note: There is no expression when the allele is maternally inherited.
Structure Level Pattern Image Note
TS21: brain Absent 1B upper left
TS21: embryo Absent 1B upper left
TS21: heart Absent 1B upper left
TS21: liver Absent 1B upper left
TS21: lung Absent 1B upper left
TS21: metanephros Absent 1B upper left
TS21: skeletal muscle Absent 1B upper left
TS21: sympathetic ganglion Absent 1B upper left
TS21: tail Absent 1B upper left
TS21: telencephalon Absent 1B upper left
TS21: spinal cord Absent 1B upper left There is no expression in the neural tube.
TS21: tail somite Absent 1B upper left There is no expression in the somites.
TS21: head Absent 1B upper left There is no expression in distal second branchial arch.
Specimen Lsh-/- paternal: embryonic day 13.5; Hellstm1Kmu/Hellstm1Kmu, Plagl1tm1Kmu/Plagl1+ (more )
Note: There is expression when the allele is paternally inherited.
Structure Level Pattern Image Note
TS21: brain Present 1B upper right
TS21: heart Present 1B upper right
TS21: liver Present 1B upper right
TS21: lung Present 1B upper right
TS21: metanephros Present 1B upper right
TS21: skeletal muscle Present 1B upper right
TS21: sympathetic ganglion Present 1B upper right
TS21: tail Present 1B upper right
TS21: telencephalon Present 1B upper right
TS21: spinal cord Present 1B upper right Expression is present in the neural tube.
TS21: tail somite Present 1B upper right Expression is present in the somites.
TS21: head Present 1B upper right Expression is present in the distal second branchial arch.
Specimen Lsh+/+ maternal: embryonic day 13.5; Plagl1tm1Kmu/Plagl1+ (more )
Note: There is no expression when the allele is maternally inherited.
Structure Level Pattern Image Note
TS21: brain Absent 1B lower left
TS21: embryo Absent 1B lower left
TS21: heart Absent 1B lower left
TS21: liver Absent 1B lower left
TS21: lung Absent 1B lower left
TS21: metanephros Absent 1B lower left
TS21: skeletal muscle Absent 1B lower left
TS21: sympathetic ganglion Absent 1B lower left
TS21: tail Absent 1B lower left
TS21: telencephalon Absent 1B lower left
TS21: spinal cord Absent 1B lower left There is no expression in the neural tube.
TS21: tail somite Absent 1B lower left There is no expression in the somites.
TS21: head Absent 1B lower left There is no expression in the distal second branchial arch.
Specimen Lsh+/+ paternal: embryonic day 13.5; Plagl1tm1Kmu/Plagl1+ (more )
Note: There is expression when the allele is paternally inherited.
Structure Level Pattern Image Note
TS21: brain Present 1B lower right
TS21: heart Present 1B lower right
TS21: liver Present 1B lower right
TS21: lung Present 1B lower right
TS21: metanephros Present 1B lower right
TS21: skeletal muscle Present 1B lower right
TS21: sympathetic ganglion Present 1B lower right
TS21: tail Present 1B lower right
TS21: telencephalon Present 1B lower right
TS21: spinal cord Present 1B lower right There is expression in the neural tube.
TS21: tail somite Present 1B lower right There is expression in the somites.
TS21: head Present 1B lower right There is expression in the distal second branchial arch.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory