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Gene Expression Data
Assay Details
Assay
Reference: J:63373 Yoshiba K, et al., Differential expression of laminin-5 subunits during incisor and molar development in the mouse. Int J Dev Biol. 2000 Apr;44(3):337-40
Assay type: Immunohistochemistry
MGI Accession ID: MGI:3575740
Gene symbol: Lamb3
Gene name: laminin, beta 3
Antibody: SEtdc3
Detection system: Secondary antibody
Assay notes: This data was discussed but not shown.
Results
Specimen E12: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS21: lower jaw incisor epithelium Present Expression is concentrated in the basement membrane and in cells of the invaginating epithelium.

Specimen E14: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: lower jaw incisor epithelium Present Regionally restricted Expression is present along the basement membrane underlying the inner dental epithelium, as well as the outer dental epithelium. The labial part of the cervical loop demonstrated a strong immunoreactivity when compared to the lingual side.
TS22: cervical loop Present Non-Uniform The labial part of the cervical loop demonstrated a strong immunoreactivity when compared to the lingual side.

Specimen E15: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: lower jaw incisor epithelium Present Regionally restricted Expression is present in the basement membrane along the outer dental epithelium, whereas weak or negligible staining is seen along the inner dental epithelium. When compared to the lingual side, the labial side of the cervical loop is intensely stained.
TS23: cervical loop Present Non-Uniform When compared to the lingual side, the labial side of the cervical loop is intensely stained.

Specimen E16.5: embryonic day 17.0 (more )
Structure Level Pattern Image Note
TS25: inner enamel epithelium Strong Regionally restricted There is intense immunoreactivity in the differentiating ameloblasts.
TS25: lower jaw incisor epithelium Strong Regionally restricted There is intense immunoreactivity in the differentiating ameloblasts.

Specimen E18: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: lower jaw molar epithelium Absent There is no expression along the inner dental epithelium.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory