Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Lmo4tm1.1Gng
Name:	LIM domain only 4; targeted mutation 1.1, Gordon N Gill
MGI ID:	MGI:3574586
Synonyms:	Lmo4-
Gene:	Lmo4  Location: Chr3:143894291-143910981 bp, - strand  Genetic Position: Chr3, 68.61 cM
Alliance:	Lmo4tm1.1Gng page

Germline Transmission:	Earliest citation of germline transmission: J:96957
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129X1/SvJ

Allele Type:    Targeted (Null/knockout) Mutation:    Intragenic deletion   Mutation details: Exons 1b and 2 were removed via cre-mediated recombination. This sequence contains the translation start site and N-terminal LIM domain. Immunohistochemical staining confirmed absence of protein in cervical spinal cord sections of mutants. (J:96957)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

4 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Lmo4 Mutation:	9 strains or lines available

Original:	J:96957 Lee SK, et al., The LIM domain-only protein LMO4 is required for neural tube closure. Mol Cell Neurosci. 2005 Feb;28(2):205-14
All:	5 reference(s)