Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Cdh17tm1Ohn
Name:	cadherin 17; targeted mutation 1, Kazuo Ohnishi
MGI ID:	MGI:3573870
Synonyms:	BILL-cadherin-
Gene:	Cdh17  Location: Chr4:11758157-11817905 bp, + strand  Genetic Position: Chr4, 5.35 cM, cytoband A2
Alliance:	Cdh17tm1Ohn page

Germline Transmission:	Earliest citation of germline transmission: J:96738
Parent Cell Line:	E14.1 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exons 16-18, which encode the transmembrane and cytoplasmic domain, were replaced with a neomycin resistance cassette. Surface labeling and subsequent immunoprecipitation demonstrated the complete absence of protein on surface of B lineage cells. (J:96738)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

3 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Cdh17 Mutation:	45 strains or lines available

Original:	J:96738 Ohnishi K, et al., Lymphocyte-expressed BILL-cadherin/cadherin-17 contributes to the development of B cells at two stages. Eur J Immunol. 2005 Mar;35(3):957-63
All:	2 reference(s)