Rb(12.Ts17<16>65Dn)2Cje MGI Mouse Cytogenetic Marker Detail - MGI:3531160 - Robertsonian translocation, Chr 12 and T17<16>Dn, Charles J Epstein 2

Rb(12.Ts17¹⁶65Dn)2Cje Cytogenetic Marker Detail

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Sequence Map

Genome coordinates not available from the current reference assembly.

Human Disease

Mouse Models

IDs

View 1 model

Click on a disease name to see all genes associated with that disease.

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Phenotype Summary

8 phenotypes from 1 allele in 2 genetic backgrounds
1 phenotype from multigenic genotypes
13 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

Summaries

All 14

Diseases 1

Phenotypes 13
Earliest

J:2300 Charles CH, et al., cDNA sequence of a growth factor-inducible immediate early gene and characterization of its encoded protein. Oncogene. 1992 Jan;7(1):187-90
Latest

J:338544 Im E, et al., Lysosomal dysfunction in Down syndrome and Alzheimer mouse models is caused by v-ATPase inhibition by Tyr(682)-phosphorylated APP betaCTF. Sci Adv. 2023 Jul 28;9(30):eadg1925

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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