Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Sult1e1tm1Song
Name:	sulfotransferase family 1E, member 1; targeted mutation 1, Wen-Chao Song
MGI ID:	MGI:3529586
Synonyms:	EST-
Gene:	Sult1e1  Location: Chr5:87723828-87739453 bp, - strand  Genetic Position: Chr5, 43.56 cM
Alliance:	Sult1e1tm1Song page

Germline Transmission:	Earliest citation of germline transmission: J:96133
Parent Cell Line:	TL1/TL-1 (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (Null/knockout) Mutation:    Insertion   Mutation details: A neo cassette was inserted into exon 3 via homologous recombination. Northern and Western blot analysis confirmed that no mRNA and protein of either normal or aberrant size were present. Sult1e1 enzyme activity in the testis was also not detected. (J:96133)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	18 assay results
In Structures Affected by this Mutation:	8 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sult1e1 Mutation:	20 strains or lines available

Original:	J:96133 Qian YM, et al., Targeted disruption of the mouse estrogen sulfotransferase gene reveals a role of estrogen metabolism in intracrine and paracrine estrogen regulation. Endocrinology. 2001 Dec;142(12):5342-50
All:	14 reference(s)