About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:9556 Lescisin KR, et al., Isolation and characterization of a novel trophoblast-specific cDNA in the mouse. Genes Dev. 1988 Dec;2(12A):1639-46
Assay type: RNA in situ
MGI Accession ID: MGI:3529243
Gene symbol: Tpbpa
Gene name: trophoblast specific protein alpha
Probe: Clone 4311
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Assay notes: Some of the sections used in these studies were cryosections, others were embedded in ester wax. It was not always clear which specimen preparation method was used for the specimens in the figures.
Results
Specimen E6.5 embryo: embryonic day 6.5 (more )
Structure Level Pattern Image Note
TS9: ectoplacental cone Present Regionally restricted Expression is present in a a few, isolated cells.

Specimen 6A/B: embryonic day 7.5 (more )
Structure Level Pattern Image Note
TS11: ectoplacental cone Present Regionally restricted 6A/B Expression is present in a subset of cells at the mesometrial end.

Specimen Maternal decidua: postnatal (more )
Note: Days 7.5-10.5 of gestation.
Structure Level Pattern Image Note
TS28: decidua Present Regionally restricted Expression is present in a few, isolated cells.

Specimen 6D: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: extraembryonic component Present Regionally restricted 6D , 6C Expression is present in outer ectoplacental cone cells, in a region just below the giant cell layer.

Specimen 6E: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: extraembryonic component Strong Regionally restricted 6E Expression is present in outer ectoplacental cone cells, in a region just below the giant cell layer.

Specimen 6F: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: extraembryonic component Strong Regionally restricted 6F Expression is present in outer ectoplacental cone cells, in a region just below the giant cell layer.

Specimen 7A: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS28: placenta Strong Regionally restricted 7A There is intense, patchy hybridization in the spongiotrophoblast; there is no hybridization to the giant cells or to the labyrinthine layer.
TS21: extraembryonic component Present Regionally restricted 7A There is some hybridization of cells in the mesometrial decidual tissue. Other studies suggest these cells are derived from the trophoblast of the conceptus.

Specimen E13.5 embryo: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: embryo Absent

Specimen 7B: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS28: placenta Strong Regionally restricted 7B There is intense, patchy hybridization in the spongiotrophoblast; there is no hybridization to the giant cells or to the labyrinthine layer.
TS23: extraembryonic component Present Regionally restricted 7B There is some hybridization of cells in the mesometrial decidual tissue. Other studies suggest these cells are derived from the trophoblast of the conceptus.

Specimen E15.5 embryo: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: embryo Absent

Specimen 7C: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS28: placenta Strong Regionally restricted 7C There is intense, patchy hybridization in the spongiotrophoblast; there is no hybridization to the giant cells or to the labyrinthine layer.
TS26: extraembryonic component Present Regionally restricted 7C There is some hybridization of cells in the mesometrial decidual tissue. Other studies suggest these cells are derived from the trophoblast of the conceptus.

Specimen E18.5 embryo: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: embryo Absent


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/25/2025
MGI 6.24
The Jackson Laboratory