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Gene Expression Data
Assay Details
Assay
Reference: J:94057 Besnard V, et al., Immunohistochemical localization of Foxa1 and Foxa2 in mouse embryos and adult tissues. Gene Expr Patterns. 2004 Dec;5(2):193-208
Assay type: Immunohistochemistry
MGI Accession ID: MGI:3527209
Gene symbol: Foxa1
Gene name: forkhead box A1
Antibody: anti-Foxa1
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 1C, +/+: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: left lung alveolus Present 1C
TS26: lung epithelium Present 1C
TS26: right lung accessory lobe alveolus Present 1C

Specimen 1D, -/-: embryonic day 18.5; Foxa1tm1Gsc/Foxa1tm1Gsc (more )
Structure Level Pattern Image Note
TS26: left lung alveolus Absent 1D
TS26: lung epithelium Absent 1D
TS26: right lung accessory lobe alveolus Absent 1D

Specimen Table 1: postnatal adult (more )
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Present
TS28: main olfactory bulb Present
TS28: tongue epithelium Present Regionally restricted Expression is in the dorsal epithelium, serous and mucous glands, and is absent in the ventral epithelium.
TS28: parotid gland Present
TS28: submandibular gland Present
TS28: ureter Present
TS28: esophagus Present Regionally restricted Expression is in the stratified squamous epithelium.
TS28: stomach Present Regionally restricted Expression is in the gastric glands and is absent in the stratified squamous epithelium.
TS28: large intestine Present Regionally restricted Expression is in the single columnar epithelium and the crypts of Lieberkuhn.
TS28: small intestine Present Regionally restricted Expression is in the single columnar epithelium and the crypts of Lieberkuhn.
TS28: liver Present Regionally restricted Expression is in the hepatocytes and bile ducts.
TS28: pancreatic duct Present Regionally restricted
TS28: pancreatic acinus Absent
TS28: islets of Langerhans Present
TS28: nasal cavity respiratory epithelium Present
TS28: adipose tissue Absent
TS28: adrenal gland Absent
TS28: arterial system Absent
TS28: bone Absent
TS28: cartilage Absent
TS28: gallbladder Absent
TS28: heart Absent
TS28: olfactory epithelium Absent
TS28: renal cortex Absent
TS28: renal medulla Absent
TS28: skeletal muscle Absent
TS28: smooth muscle tissue Absent
TS28: spleen Absent
TS28: thymus Absent
TS28: venous system Absent
TS28: olfactory gland Absent Expression is absent in the olfactory glands.
TS28: pharynx Present Regionally restricted Expression is in the columnar epithelium and the mucous acini.
TS28: trachea Present Regionally restricted Expression is in the tracheal glands and the stratified squamous epithelium.
TS28: bronchus Present Regionally restricted Expression is in the bronchiolar epithelium and the alveolar epithelium (type II cells).
TS28: thyroid gland Present
TS28: metanephros Present Regionally restricted Expression is in the pyramid and calyx (columnar and transitional epithelium).
TS28: bladder Present Regionally restricted Expression is in the transitional epithelium.

Specimen Table 1 male: postnatal adult (more )
Structure Level Pattern Image Note
TS28: epididymis Absent
TS28: penis Absent
TS28: testis Absent
TS28: anterior prostatic epithelium Present coagulating gland (cuboidal epithelium)
TS28: epithelium of seminal vesicle Present vesicular gland (columnar epithelium)
TS28: prostate gland Present
TS28: prostatic urethra Present

Specimen Table 1 female: postnatal adult (more )
Structure Level Pattern Image Note
TS28: mammary gland Present Regionally restricted Expression is present in the lactiferous ducts and is absent in the glandular alveoli.
TS28: vagina squamous epithelium Present
TS28: ovary Absent
TS28: uterine gland Absent
TS28: uterine horn epithelium Absent endometrium
TS28: endometrium luminal epithelium Absent uterus columnar epithelium

Specimen 2A: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: hepatic primordium Present 2A
TS17: hindgut Present 2A
TS17: laryngo-tracheal groove Present 2A
TS17: lung Present 2A
TS17: neural tube Present 2A
TS17: notochord Present 2A
TS17: pharynx Present 2A
TS17: tail neural tube Present 2A

Specimen 2C: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: liver Present 2C
TS21: lung Present 2C
TS21: stomach Present 2C
TS21: tongue epithelium Present Regionally restricted 2C Expression is in the dorsal epithelium.
TS21: submandibular gland primordium Weak 2C
TS21: midbrain Present Regionally restricted 2C Expression is ventral.

Specimen 3A: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: esophagus Present 3A
TS23: intestine Present 3A
TS23: liver Present 3A
TS23: lung Present 3A
TS23: pancreas Present 3A
TS23: stomach Present 3A
TS23: tongue epithelium Present Regionally restricted 3A Expression is in the dorsal epithelium.
TS23: spinal cord floor plate Present Regionally restricted 3A Expression is at the level of the fore- and hindlimb.
TS23: midbrain Present Regionally restricted 3A Expression is in the ventral midbrain.
TS23: hypothalamus Present 3A
TS23: nasal cavity Very strong 3A
TS23: thyroid gland Present 3A

Specimen 3B: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: 4th ventricle Present Regionally restricted 3B Expression is in the periventricular region.
TS23: hypothalamus Present 3B
TS23: midbrain Present Regionally restricted 3B Expression is in the ventral midbrain.

Specimen 3C: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: submandibular gland primordium Present 3C
TS23: thyroid gland Present 3C

Specimen 3D: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: renal pelvis Present Regionally restricted 3D Expression is in the epithelium.

Specimen Not Shown: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: esophagus Present
TS26: hypothalamus Present
TS26: intestine Present
TS26: liver Present
TS26: lung Present
TS26: stomach Present
TS26: submandibular gland Present
TS26: thyroid gland Present
TS26: tongue epithelium Present Regionally restricted Expression is in the dorsal epithelium.
TS26: spinal cord floor plate Present Regionally restricted Expression is at the level of the fore- and hindlimb.
TS26: midbrain Present Regionally restricted Expression is in the ventral midbrain.
TS26: nasal cavity Very strong
TS26: 4th ventricle Present Regionally restricted Expression is in the periventricular region.
TS26: renal pelvis Present Regionally restricted Expression is in the epithelium.
TS26: bladder Present Regionally restricted Expression is in the epithelium.
TS26: pancreas Absent

Specimen 4A: postnatal adult (more )
Structure Level Pattern Image Note
TS28: telencephalon Present Regionally restricted 4A Expression is ventral.
TS28: main olfactory bulb Present 4A

Specimen 4C: postnatal adult (more )
Structure Level Pattern Image Note
TS28: hippocampus Present 4C

Specimen 4E: postnatal adult (more )
Structure Level Pattern Image Note
TS28: hypothalamus Present 4E
TS28: midbrain Present Regionally restricted 4E Expression is motor neurons in the ventral midbrain.

Specimen 4G: postnatal adult (more )
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Present 4G Expression is nuclear.

Specimen 5A: postnatal adult (more )
Structure Level Pattern Image Note
TS28: tongue epithelium Present Regionally restricted 5A Expression is in the dorsal epithelium
TS28: taste bud Absent 5A
TS28: tongue muscle Absent 5A

Specimen 5C: postnatal adult (more )
Structure Level Pattern Image Note
TS28: tongue Present Regionally restricted 5C Expression is in serous and mucous glands.

Specimen 5E: postnatal adult (more )
Structure Level Pattern Image Note
TS28: tongue epithelium Weak Regionally restricted 5E Expression is in the ventral epithelium.

Specimen 5G: postnatal adult (more )
Structure Level Pattern Image Note
TS28: submandibular gland Present Regionally restricted 5G Expression is in the acini and in the excretory ducts.

Specimen 5I: postnatal adult (more )
Structure Level Pattern Image Note
TS28: parotid gland Present Regionally restricted 5I Expression is in the acini and in the excretory ducts.

Specimen 6A: postnatal adult (more )
Structure Level Pattern Image Note
TS28: esophagus Present Regionally restricted 6A Expression is in the epithelium.

Specimen 6C: postnatal adult (more )
Structure Level Pattern Image Note
TS28: stomach Present Regionally restricted 6C Expression is in the glandular portion.

Specimen 6E: postnatal adult (more )
Structure Level Pattern Image Note
TS28: small intestine Present Regionally restricted 6E Expression is in the crypts of lieberkuhn and in the lining epithelium.

Specimen 6G: postnatal adult (more )
Structure Level Pattern Image Note
TS28: large intestine Present Regionally restricted 6G Expression is in the intestinal glands and in the epithelium.

Specimen 7A: postnatal adult (more )
Structure Level Pattern Image Note
TS28: gallbladder Absent 7A

Specimen 7C: postnatal adult (more )
Structure Level Pattern Image Note
TS28: liver Present Regionally restricted 7C Expression is in hepatocytes and bile ducts.

Specimen 7E: postnatal adult (more )
Structure Level Pattern Image Note
TS28: pancreas Present Regionally restricted 7E Expression is in the ducts.
TS28: islets of Langerhans Present 7E

Specimen 8A: postnatal adult (more )
Structure Level Pattern Image Note
TS28: nasal cavity respiratory epithelium Strong 8A

Specimen 8C: postnatal adult (more )
Structure Level Pattern Image Note
TS28: pharynx Present Regionally restricted 8C Expression is in the epithelium and mucous glands.

Specimen 8E: postnatal adult (more )
Structure Level Pattern Image Note
TS28: trachea Present Regionally restricted 8E Expression is in the epithelium and glands.

Specimen 8G: postnatal adult (more )
Structure Level Pattern Image Note
TS28: lung Present Regionally restricted 8G Expression is in epithelial cells in both conducting airways and in alveolar type II cells.

Specimen 8I: postnatal adult (more )
Structure Level Pattern Image Note
TS28: thyroid gland Strong Regionally restricted 8I Expression is in a small subset of follicular cells.

Specimen 9A: postnatal adult (more )
Structure Level Pattern Image Note
TS28: metanephros Present Regionally restricted 9A Expression is in the epithelial cells lining the calyx and pyramid.

Specimen 9C: postnatal adult (more )
Structure Level Pattern Image Note
TS28: ureter Present Regionally restricted 9C Expression is in the transitional epithelium lining the ureter.

Specimen 9E: postnatal adult (more )
Structure Level Pattern Image Note
TS28: bladder Present Regionally restricted 9E Expression is in the epithelium.

Specimen 10A: postnatal adult (more )
Structure Level Pattern Image Note
TS28: male reproductive system Present Regionally restricted 10A Expression is in the coagulating gland.

Specimen 10C: postnatal adult (more )
Structure Level Pattern Image Note
TS28: male reproductive system Present Regionally restricted 10C Expression is in the vesicular gland.

Specimen 10E: postnatal adult (more )
Structure Level Pattern Image Note
TS28: testis Absent 10E

Specimen 10G: postnatal adult (more )
Structure Level Pattern Image Note
TS28: male reproductive system Present Regionally restricted 10G Expression is in the prostatic urethral wall.

Specimen 10I: postnatal adult (more )
Structure Level Pattern Image Note
TS28: prostate gland Present 10I

Specimen 11A: postnatal adult (more )
Structure Level Pattern Image Note
TS28: ovary Absent 11A

Specimen 11C: postnatal adult (more )
Structure Level Pattern Image Note
TS28: uterus Absent 11C

Specimen 11E: postnatal adult (more )
Structure Level Pattern Image Note
TS28: epithelium of vagina Present 11E Expression is in the vaginal epithelium.

Specimen 11G: postnatal adult (more )
Structure Level Pattern Image Note
TS28: mammary gland Present Regionally restricted 11G Expression is in the lactiferous ducts and is absent in the alveoli.


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory